Author

H. Niu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 4 Bioengineering· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Assay:proteomics· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

F. Gao· 5 shared G. Chen· 4 shared X. Li· 4 shared B. Zhu· 3 shared G. Zhu· 2 shared J. Shen· 2 shared J. Yuan· 2 shared L. Gao· 2 shared

Activity by Year

2017-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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5 shared papersImmunology

F. Gao

Mutual co-authors in cluster

Author profile →

11 papers

Recent·Most cited

Cdc13 exhibits dynamic DNA strand exchange in the presence of telomeric DNA

D. G. Nickens, Z. Feng, J. Shen, S. J. Gray, R. H. Simmons, H. Niu, M. L. Bochman

This study shows that Cdc13 can dynamically exchange DNA strands in the presence of telomeric DNA, revealing a mechanism for its movement at telomeres.

Nucleic Acids Research · Apr 13, 2024Peer-reviewedBiochemistry

Camel milk affects serum metabolites by modulating the intestinal microflora

H. Yue, J. Zhang, R. Wang, L. Zhao, Y. Kou, R. Li, Z. Yang, Y. Qian, X. Li, X. Wang, P. Yasheng, J. Wu, X. Xing, L. Xie, H. Niu, , F. Gao

This study shows that camel milk modulates gut microbiota and serum metabolites in rats, with beneficial bacteria and metabolites resembling those of healthy individuals.

bioRxiv · Dec 18, 2023 · PreprintMicrobiology

Enhancement of Cell Adhesion by Anaplasma phagocytophilum Nucleolin-interacting Protein AFAP

H. Tang, J. Zhu, S. Wu, H. Niu

This study identifies AFAP as a bacterial protein that enhances cell adhesion by interacting with host nucleolin, providing insights into the mechanism of A. phagocytophilum-induced cell adhesion in HGA.

bioRxiv · May 17, 2022Microbiology

SARS-CoV-2 variant B.1.1.7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response

C. Xiao, L. Mao, Z. Wang, G. Zhu, L. Gao, J. Su, X. Chen, J. Yuan, Y. Hu, Z. Yin, J. Xie, W. Ji, H. Niu, F. Gao, O. J. Luo, , G. Chen

This study identifies mutations in SARS-CoV-2 variant B.1.1.7 that reduce HLA-A2 restricted CD8+ T cell epitope binding and impair cellular immune responses.

iScience · Mar 1, 2022Peer-reviewedImmunology

Lupus Gut Microbiota Transplants Cause Autoimmunity and Inflammation

Y. Ma, R. Guo, Y. Sun, X. Li, L. He, Z. Li, G. J. Silverman, G. Chen, F. Gao, J. Yuan, Q. Wei, M. Li, L. Lu, H. Niu

This study shows that transferring gut microbiota from SLE patients to germ-free mice induces lupus-like features, suggesting a causal role for gut microbiota in SLE pathogenesis.

bioRxiv · Aug 15, 2021Immunology

Augmenting Neutralization breadth against Diverse HIV-1 by increasing the Ab-Ag interface on V2

N. Gao, Y. Gai, L. Meng, C. Wang, W. Wang, X. Li, T. Gu, M. K. Louder, N. A. Doria-Rose, K. Wiehe, A. F. Nazzari, A. S. Olia, J. Gorman, R. Rawi, W. Wu, , F. Gao

This study identifies a lineage of antibodies from infected rhesus macaques that neutralize 54% of HIV-1 strains by expanding the antibody-Env interface around the V2 loop.

bioRxiv · Aug 7, 2021 · PreprintImmunology

Sustained Oxygenation Accelerates Diabetic Wound Healing by Simultaneously Promoting Epithelialization and Angiogenesis, and Decreasing Tissue Inflammation

Y. Guan, H. Niu, Z. Liu, Y. Dang, J. Shen, M. Zayed, L. Ma, J. Guan

This study shows sustained oxygenation improves diabetic wound healing by enhancing epithelialization, angiogenesis, and reducing inflammation without drugs.

bioRxiv · Apr 6, 2021Bioengineering

Identification of age and ethnicity specific gene expression biomarkers for immune aging

Y. Hu, Y. Xu, L. Mao, J. Xiang, W. Lei, G. Zhu, Y. Hu, H. Niu, F. Gao, L. Gao, L. Huang, O. J. Luo, G. Chen

This study identifies age and ethnicity-specific gene expression biomarkers for immune aging using transcriptomic data from peripheral blood mononuclear cells.

bioRxiv · Feb 22, 2021 · PreprintImmunology

Production of SARS-CoV-2 virus-like particles in insect cells

Y. mi, T. Xie, B. Zhu, J. tan, X. Li, Y. Luo, F. Li, H. Niu, J. Han, W. Lv, J. Wang

This study produces SARS-CoV-2 virus-like particles in insect cells for vaccine development and research.

bioRxiv · Jan 30, 2021Bioengineering

Introducing RpsA Point Mutation Δ438A or D123A into the Chromosome of M. tuberculosis Confirms its Role in Causing Resistance to Pyrazinamide

W. Shi, P. Cui, H. Niu, S. Zhang, T. Tonjum, B. Zhu, Y. Zhang

The paper introduces RpsA mutations Δ438A and D123A into M. tuberculosis to confirm their role in pyrazinamide resistance.

bioRxiv · Jan 10, 2019Microbiology

Identification of drug candidates that enhance pyrazinamide activity from a clinical drug library

H. Niu, C. Ma, P. Cui, W. Shi, S. Zhang, J. Feng, D. Sullivan, B. Zhu, W. Zhang, Y. Zhang

This study identifies drugs that enhance pyrazinamide's anti-persister activity by screening a clinical drug library against M. tuberculosis cultures enriched with persisters.

bioRxiv · Mar 4, 2017Microbiology