Allosteric capsid inhibitors and their escape mutants drive HIV-1 sensing
Kate L. Morling, Morten L. Govasli, Ben Graham, J.M. Warne, Lauren Harrison, Lucy Thorne, Lydia S. Newton, Joshua Maw, Emma Touizer, Rebecca P. Sumner, Sally J. Oxenford, Joanna Rowley, Dara Annett, David A. Jacques, Till Böcking, , Greg J. Towers
This study investigates allosteric capsid inhibitors and their resistance mutants, showing they trigger innate immune responses and may reduce HIV-1 transmission.
bioRxiv · Aug 26, 2026 · PreprintMicrobiology