Author

Valeria Pingitore

University College LondonORCID 0009-0001-0997-9628Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

David L. SelwoodiD· 3 shared A. W. Edith ChaniD· 1 shared Adrian James ThrasheriD· 1 shared Aura Hare· 1 shared Ben Graham· 1 shared Bethan J. CritchleyiD· 1 shared Chih-Yao ChungiD· 1 shared Dara Annett· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

David L. SelwoodORCID

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3 papers

Recent·Most cited

Cell BiologyMolecular TherapyPeer-reviewedAug 3, 2026

A modified cyclosporine enhances lentivector transduction ex vivo and in vivo by degrading IFITM3

Dara Annett, Bethan J. Critchley, Kate L. Morling…·Greg J. Towers

BG147 enhances lentivector transduction in HSPCs ex vivo and in mouse photoreceptors in vivo by degrading IFITM3.

DOI 10.1016/j.ymthe.2026.07.056

mousebulk RNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedMay 26, 2026

Pathogenic variants in autophagy-tethering factor EPG5 drive neurodegeneration through mitochondrial dysfunction and innate immune activation

Kritarth Singh, Hormos Salimi Dafsari, Olivia Gillham…·Michael R. Duchen

This study identifies EPG5 mutations causing neurodegeneration via mitochondrial dysfunction and innate immune activation in patient-derived cells.

4 citationstop 2%

humanbulk RNA-seq

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Cell BiologybioRxivPreprintApr 15, 2024

Development of the ULK1-Recruiting Chimeras (ULKRECs) to enable proximity-induced and ULK1-dependent degradation of mitochondria

Niyaz Zaman, Natasha Aley, Valeria Pingitore…·Robin Ketteler

This paper introduces ULK1-Recruiting Chimeras (ULKRECs) that induce ULK1-dependent mitophagy, showing efficacy in Parkinson's fibroblasts independent of the PRKN/PINK axis.

3 citations

humanexperimental assay

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