Author

C. A. Winkler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pathology· 3 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Approach:experimental assay· 4 Organism:mouse· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Z. Rosenberg· 4 shared J. B. Kopp· 4 shared K. Z. Latt· 4 shared T. Yoshida· 4 shared Y. Zhao· 4 shared S. Shrivastav· 3 shared B. A. Santo· 2 shared J. Heymann· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersPathology

A. Z. Rosenberg

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

APOL1 kidney risk variants in glomerular diseases modeled in transgenic mice

T. Yoshida, K. Z. Latt, B. A. Santo, S. Shrivastav, Y. Zhao, P. Fenaroli, J.-Y. Chung, S. M. Hewitt, V. M. Tutino, P. Sarder, A. Z. Rosenberg, C. A. Winkler, J. B. Kopp

This paper uses two transgenic mouse models to study APOL1 risk variants' effects on glomerular disease, identifying shared and distinct transcriptional changes in podocytes.

bioRxiv · Mar 27, 2023Pathology

HIV viral protein R induces loss of DCT1-type renal tubules

K. Z. Latt, T. Yoshida, S. Shrivastav, A. Abedini, J. M. Reece, Z. Sun, H. Lee, K. Okamoto, P. Dagur, J. Heymann, Y. Zhao, J.-Y. Chung, S. Hewitt, P. A. Jose, K. Lee, , J. B. Kopp

This study shows HIV Vpr reduces DCT1-type renal tubules in mice, leading to salt wasting via apoptosis dysregulation of Slc12a3+ Pvalb+ cells.

bioRxiv · Feb 2, 2023 · PreprintPathology

PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy

T. Yoshida, K. Z. Latt, A. Z. Rosenberg, B. A. Santo, K. Myakala, Y. Ishimoto, Y. Zhao, S. Shrivastav, B. A. Jones, X. Yang, X. Wang, V. M. Tutino, P. Sarder, M. Levi, K. Okamoto, , J. B. Kopp

This study shows that PKR inhibition reduces mitochondrial dysfunction and ameliorates HIV-associated nephropathy in transgenic mice using single-nucleus and bulk RNA-seq.

bioRxiv · Oct 3, 2022Pathology

Urine single cell RNA-sequencing in focal segmental glomerulosclerosis reveals inflammatory signatures in immune cells and podocytes

K. Z. Latt, J. Heymann, J. H. Jessee, A. Z. Rosenberg, C. C. Berthier, S. Eddy, T. Yoshida, Y. Zhao, V. Chen, G. W. Nelson, M. Cam, P. Kumar, M. Mehta, M. C. Kelly, M. Kretzler, , J. B. Kopp

This study uses urine single cell RNA-sequencing to identify inflammatory signatures in immune cells and podocytes in FSGS, suggesting potential for non-invasive diagnosis and biomarker discovery.

bioRxiv · Oct 18, 2020Immunology

Effects of anthropogenic wildfire activity in low elevation Pacific island vegetation communities in French Polynesia

E. A. Newman, C. A. Winkler, D. H. Hembry

The paper examines the effects of anthropogenic wildfire on vegetation in Moorea, French Polynesia, finding no significant impact on species richness but potential increases in invasive species abundance.

bioRxiv · Jun 1, 2018Ecology