Author

C. Castonguay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

O. A. Kugler-Umana· 2 shared S. L. Swain· 2 shared A. Marshak-Rothstein· 1 shared B. Stadinski· 1 shared E. Huseby· 1 shared G. C. Weaver· 1 shared J. Liang· 1 shared L. J. Stern· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

O. A. Kugler-Umana

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Peptide Avidity for TCR on CD4 Effectors Determines the Extent of Memory Generation

M. C. Jones, C. Castonguay, P. P. Nanaware, G. C. Weaver, B. Stadinski, O. A. Kugler-Umana, E. Huseby, L. J. Stern, P. J. Devarajan, S. L. Swain

This study shows that higher peptide antigen avidity for TCR on CD4 effector cells leads to increased memory cell generation and better protection against influenza rechallenge.

bioRxiv · May 9, 2022Immunology

IgD+ Age-Associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

O. A. Kugler-Umana, W. Zhang, Y. Kuang, J. Liang, C. Castonguay, S. L. Tonkonogy, A. Marshak-Rothstein, P. Devarajan, S. L. Swain

The paper identifies IgD+CD21-CD23- age-associated B cells as precursors of infection-induced B cells in aged mice, which provide protective antibody responses and can be induced by inactivated vaccines.

bioRxiv · Feb 4, 2022Immunology