Author

O. A. Kugler-Umana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Castonguay· 2 shared S. L. Swain· 2 shared A. Marshak-Rothstein· 1 shared B. Stadinski· 1 shared E. Huseby· 1 shared G. C. Weaver· 1 shared J. Liang· 1 shared L. J. Stern· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

C. Castonguay

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2 papers

Recent·Most cited

ImmunologybioRxivMay 9, 2022

Peptide Avidity for TCR on CD4 Effectors Determines the Extent of Memory Generation

M. C. Jones, C. Castonguay, P. P. Nanaware…·S. L. Swain

This study shows that higher peptide antigen avidity for TCR on CD4 effector cells leads to increased memory cell generation and better protection against influenza rechallenge.

DOI 10.4049/jimmunol.2200337

mouseproteomics

𝕏 PostBluesky

ImmunologybioRxivFeb 4, 2022

IgD+ Age-Associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

O. A. Kugler-Umana, W. Zhang, Y. Kuang…·S. L. Swain

The paper identifies IgD+CD21-CD23- age-associated B cells as precursors of infection-induced B cells in aged mice, which provide protective antibody responses and can be induced by inactivated vaccines.

DOI 10.1111/acel.13705

mouseflow cytometry

𝕏 PostBluesky