Phenethylamine-producing gut bacteria induces diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis
L. Zhai, C. Huang, Z. Ning, Y. Zhang, M. Zhuang, W. Yang, X. Wang, J. Wang, E. L. Zhang, H. Xiao, L. Zhao, Y. Y. Lam, C. F. W. Chow, J. Huang, S. Yuan, , Z.-x. Bian
This study identifies Ruminococcus gnavus as a gut bacterium that contributes to IBS-D by increasing serotonin biosynthesis through phenethylamine production.
bioRxiv · Mar 5, 2022 · PreprintMicrobiology