Author

R. Classens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

L. Querol Cano· 3 shared A. Rodgers Furones· 2 shared A. B. van Spriel· 1 shared A. van Duffelen· 1 shared A. van Spriel· 1 shared B. Coenen· 1 shared C. G. Spruijt· 1 shared C. Koenig· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

L. Querol Cano

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Galectin-9 regulates dendritic cell polarity and uropod contraction by modulating RhoA activity

G. Franken, J. Cuenca-Escalona, I. F. Stehle, V. van Reijmersdal, A. Rodgers Furones, R. R. Gokhale, R. Classens, S. diBlasio, Y. Dolen, A. van Spriel, L. Querol Cano

This study shows galectin-9 regulates dendritic cell migration by modulating RhoA activity and CD44-mediated rear contractility in both humans and mice.

bioRxiv · Oct 30, 2023 · PreprintImmunology

Cofilin-Driven Nuclear Deformation Drives Dendritic Cell Migration through the Extracellular Matrix

H. Warner, G. Franciosa, G. van der Borg, F. Faas, C. Koenig, R. de Boer, R. Classens, S. Maassen, M. Baranov, S. Mahajan, D. D. Dabral, B. Coenen, F. Bianchi, N. van Hilten, H. J. Risselada, , G. V. van den Bogaart

This study shows that cofilin-1 phosphorylation drives nuclear deformation and enhances dendritic cell migration through extracellular matrix.

bioRxiv · Jul 10, 2023Cell Biology

Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells

R. Santalla Mendez, A. Rodgers Furones, R. Classens, M. Haverdil, M. Canela Capdevila, A. van Duffelen, M. ter Beest, C. G. Spruijt, M. Vermeulen, A. B. van Spriel, L. Querol Cano

This study identifies galectin-9 as essential for cytokine trafficking in dendritic cells by interacting with Vamp-3, preventing cytokine accumulation in the Golgi and promoting secretion.

bioRxiv · May 13, 2022 · PreprintCell Biology