Author

C. J. Greenbaum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Speake· 3 shared A. Arnett· 1 shared A. E. Wiedeman· 1 shared A. Perdigoto· 1 shared B. Khor· 1 shared C. Evans-Molina· 1 shared E. A. James· 1 shared E. K. Sims· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersImmunology

C. Speake

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Author profile →

3 papers

Recent·Most cited

Permutational immune analysis reveals architectural similarities between inflammaging, Down syndrome and autoimmunity

K. Lambert, K. G. Moo, A. Arnett, G. Goel, K. J. Flynn, C. Speake, A. E. Wiedeman, C. J. Greenbaum, S. A. Long, R. Partridge, J. H. Buckner, B. Khor

The paper uses permutational analysis to reveal advanced immune aging in Down syndrome and type 1 diabetes.

bioRxiv · Sep 13, 2021 · PreprintImmunology

Citrullination of glucokinase linked to autoimmune diabetes

M.-L. Yang, S. Horstman, R. Gee, P. Guyer, T. Lam, J. Kanyo, A. Perdigoto, C. Speake, C. J. Greenbaum, L. Overbergh, R. Kibbey, K. C. Herold, E. A. James, M. J. Mamula

This study identifies citrullination of glucokinase as an inflammatory-driven PTM that triggers autoimmunity and impairs glucose metabolism in Type 1 diabetes.

bioRxiv · Apr 28, 2021Immunology

Abnormalities in Proinsulin Processing in Islets from Individuals with Longstanding T1D

E. K. Sims, J. Nyalwidhe, F. Syed, H. T. Bahnson, L. Haataja, C. Speake, M. Morris, R. G. Mirmira, J. Nadler, T. L. Mastracci, P. Arvan, C. J. Greenbaum, C. Evans-Molina

The paper investigates proinsulin processing abnormalities in T1D islets, finding reduced processing enzymes and cytokine-induced expression changes.

bioRxiv · Feb 8, 2019Pathology