Author

E. K. Sims

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

E. S. Nakayasu· 2 shared F. Huang· 2 shared R. G. Mirmira· 2 shared S. Sarkar· 2 shared A. Chakraborty· 1 shared B.-J. M. Webb-Robertson· 1 shared C. Evans-Molina· 1 shared C. J. Greenbaum· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

E. S. Nakayasu

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Author profile →

3 papers

Recent·Most cited

Inhibition of the Eukaryotic Initiation Factor-2-α Kinase PERK Decreases Risk of Autoimmune Diabetes in Mice

C. Muralidharan, F. Huang, J. R. Enriquez, J. E. Wang, J. B. Nelson, T. Nargis, S. C. May, A. Chakraborty, K. T. Figatner, S. Navitskaya, C. M. Anderson, V. Calvo, D. Surguladze, M. J. Mulvihill, X. Yi, , R. G. Mirmira

This study shows that inhibiting PERK reduces autoimmune diabetes risk in mice by decreasing β cell immunogenicity and improving islet function.

bioRxiv · Oct 6, 2023Cell Biology

Meta-analysis refinement of plasma extracellular vesicle composition identifies proplatelet basic protein as a signaling messenger in type 1 diabetes

M. C. Vallejo, S. Sarkar, E. C. Elliott, H. R. Henry, F. Huang, S. H. Payne, S. Ramanadham, E. K. Sims, T. O. Metz, R. Mirmira, E. S. Nakayasu

bioRxiv · Sep 28, 2022 · PreprintCell Biology

Abnormalities in Proinsulin Processing in Islets from Individuals with Longstanding T1D

E. K. Sims, J. Nyalwidhe, F. Syed, H. T. Bahnson, L. Haataja, C. Speake, M. Morris, R. G. Mirmira, J. Nadler, T. L. Mastracci, P. Arvan, C. J. Greenbaum, C. Evans-Molina

The paper investigates proinsulin processing abnormalities in T1D islets, finding reduced processing enzymes and cytokine-induced expression changes.

bioRxiv · Feb 8, 2019Pathology