Author

C. Kassab

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. B. Heimberger· 2 shared G. Draetta· 2 shared J. Hu· 2 shared A. Alsuliman· 1 shared A. D. Miller· 1 shared A. Heimberger· 1 shared A. K. LeBlanc· 1 shared A. K. Nunez Cortes· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

A. B. Heimberger

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Author profile →

3 papers

Recent·Most cited

Immune landscape of a genetically-engineered murine model of glioma relative to human glioma by single-cell sequencing

D. B. Zamler, T. Shingu, L. M. Kahn, C. Kassab, M. Ott, K. Tomczak, J. Liu, Y. Li, I. P. Lai, C. Yee, K. Rai, A. B. Heimberger, G. Draetta, J. Hu

This study compares the immune landscape of a genetically-engineered murine glioma model to human glioma using single-cell sequencing, finding similar immunosuppressive features but differences in immune cell composition between mouse models and human samples.

bioRxiv · May 11, 2020 · PreprintCancer Biology

Inhibition of the av integrin-TGF-b axis improves natural killer cell function against glioblastoma stem cells

H. Shaim, M. Hernandez Sanabria, R. Basar, F. Wang, M. Daher, D. Zamler, J. Gumin, K. Gabrusiewicz, Q. Miao, J. Dou, A. Alsuliman, L. Kerbauy, S. Acharya, V. Mohanty, P. Banerjee, , K. Rezvani

The paper shows that inhibiting the integrin-TGF-β axis enhances NK cell function against glioblastoma stem cells, suggesting it as a therapeutic target.

bioRxiv · Mar 30, 2020 · PreprintImmunology

Comparative molecular life history of spontaneous canine and human gliomas

S. B. Amin, K. J. Anderson, C. E. Boudreau, E. Martinez-Ledesma, E. Kocavakuk, K. C. Johnson, F. P. Barthel, F. S. Varn, C. Kassab, X. Ling, H. Kim, M. Barter, C. Y. Ngan, M. Chapman, J. W. Koehler, , R. G. Verhaak

This study compares molecular profiles of canine and human gliomas to identify conserved mutational processes and similarities in tumor development.

bioRxiv · Jun 17, 2019Cancer Biology