Author

K. Tomczak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

K. Rai· 3 shared A. B. Heimberger· 1 shared A. Futreal· 1 shared A. J. Lazar· 1 shared A. Raman· 1 shared C. Bernatchez· 1 shared C. Creasy· 1 shared C. Kassab· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

K. Rai

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Author profile →

3 papers

Recent·Most cited

Single-cell Characterization of Acute Myeloid Leukemia and its Microenvironment Following PD-1 Blockade Based Therapy

H. A. Abbas, D. Hao, K. Tomczak, P. Baroodia, J. Im, P. K. Reville, Z. Alaniz, W. Wang, R. Wang, F. Wang, G. Al-Atrash, K. Takahashi, J. Ning, M. Ding, J. Matthews, , A. Futreal

This study analyzes single-cell RNA and TCR profiles from AML patients before and after PD-1 blockade therapy to identify factors influencing response and resistance.

bioRxiv · Sep 3, 2020Cancer Biology

Immune landscape of a genetically-engineered murine model of glioma relative to human glioma by single-cell sequencing

D. B. Zamler, T. Shingu, L. M. Kahn, C. Kassab, M. Ott, K. Tomczak, J. Liu, Y. Li, I. P. Lai, C. Yee, K. Rai, A. B. Heimberger, G. Draetta, J. Hu

This study compares the immune landscape of a genetically-engineered murine glioma model to human glioma using single-cell sequencing, finding similar immunosuppressive features but differences in immune cell composition between mouse models and human samples.

bioRxiv · May 11, 2020 · PreprintCancer Biology

Bivalent and Broad Chromatin Domains Regulate Pro-metastatic Drivers in Melanoma

C. Terranova, M. Tang, M. Maitituoheti, A. Raman, J. Schulz, S. Amin, E. Orouji, K. Tomczak, S. Sarkar, J. Oba, C. Creasy, C.-J. Wu, D. Zhao, K. Chen, L. E. Haydu, , K. Rai

The paper identifies bivalent chromatin states and broad H3K4me3 domains associated with pro-metastatic drivers in melanoma using ChIP-sequencing data from tumor samples and cell lines.

bioRxiv · Aug 1, 2019 · PreprintCancer Biology