Author

C. Kovacs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

E. Benko· 3 shared D. Chan· 2 shared R. B. Jones· 2 shared R. Truong· 2 shared Y. Ren· 2 shared A. Bosque· 1 shared A. Imran· 1 shared A. Macedo· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

E. Benko

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Author profile →

4 papers

Recent·Most cited

A Subset of HIV 1 Controllers Lack Cortical Actin Disruption Indicative of ARP2/3 Inhibition.

R. L. F. O'Brien, C. Kovacs

The paper identifies that some HIV-1 controllers lack actin disruption typical of ARP2/3 inhibition, suggesting a protective mechanism against immune dysfunction.

bioRxiv · Jul 27, 2023 · PreprintImmunology

Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV

V. A. Matveev, E. Z. Mihelic, E. Benko, P. Budylowski, S. Grocott, T. Lee, C. S. Korosec, K. Colwill, H. Stephenson, R. Law, L. A. Ward, S. Sheikh-Mohamed, G. Mailhot, M. Delgado-Brand, A. Pasculescu, , M. Ostrowski

This study evaluates the immunogenicity of COVID-19 vaccines in older people with HIV and their impact on HIV reservoirs, finding that three doses are needed for optimal neutralizing responses but vaccines may increase HIV reservoirs in those with persistent viremia.

bioRxiv · Jun 14, 2023Immunology

Selective BCL-XLAntagonists Eliminate Infected Cells from a Primary Cell Model of HIV Latency but not from Ex Vivo Reservoirs

Y. Ren, s. h. huang, A. Macedo, A. Ward, W. Conce, T. Klevorn, L. Leyre, D. Chan, R. Truong, T. Rohwetter, P. Zumbo, F. Dundar, D. Betel, C. Kovacs, E. Benko, , B. Jones

This study shows BCL-XL antagonists reduce HIV in a cell model of latency but not in ex vivo reservoirs, suggesting resistance in true reservoir cells.

bioRxiv · Nov 25, 2020 · PreprintMicrobiology

Susceptibility to Neutralization by Broadly Neutralizing Antibodies Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs

Y. Ren, M. Korom, R. Truong, D. Chan, S.-h. Huang, C. Kovacs, E. Benko, J. T. Safrit, J. Lee, H. Garban, R. Apps, H. Goldstein, R. M. Lynch, R. B. Jones

This study examines the correlation between neutralization breadth and infected-cell binding of broadly neutralizing antibodies against HIV reactivated from latent reservoirs.

bioRxiv · May 25, 2018Immunology