C. Ku

Life Cycle and Morphogenetic Differentiation in Heteromorphic Cell Types of a Cosmopolitan Marine Microalga

The paper investigates the life cycle and morphogenetic differentiation of decoupled cells in O. huxleyi, showing they can revert to calcified form without viral pressure and exhibit distinct transcriptomic and ultrastructural features.

Cathepsin X is a conserved cell death protein involved in algal response to environmental stress

The paper identifies cathepsin X as a conserved cell death protein in algae involved in responses to environmental stress through transcriptome analysis and mutant studies.

Widespread distribution and evolution of poxviral entry-fusion complex proteins in giant viruses

This study identifies and analyzes the distribution and evolution of EFC protein homologs across poxviruses and other giant viruses in Nucleocytoviricota, revealing conserved structural features and suggesting an ancient origin for these proteins.

Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics

The paper uses single-cell transcriptomics to reveal daily viral infection turnover in algal blooms, showing consistent infection proportions and calcified infected cells.

New hypotheses of cell type diversity and novelty from comparative single cell and nuclei transcriptomics in echinoderms

This paper develops a gene expression atlas of the bat star using snRNA-seq and compares it to sea urchin embryos to reinterpret the evolution of cell types.

Single-cell transcriptomics unveils xylem cell development and evolution

This study uses single-cell transcriptomics to analyze xylem cell development and evolution across four angiosperms, revealing conserved and variable lineage patterns.

Clinically applicable histopathological diagnosis system for gastric cancer detection using deep learning

This paper develops a deep learning system for gastric cancer detection using histopathological images, achieving high sensitivity and robust performance across different scanners.

Tracking infection dynamics at single-cell level reveals highly resolved expression programs of a large virus infecting algal blooms

The paper uses single-cell transcriptomics to track infection dynamics of a virus in algal blooms, identifying novel viral genetic programs and host transcriptome changes during infection.

Bacterial virulence against an oceanic bloom-forming phytoplankter is mediated by algal DMSP

The paper shows that DMSP from the alga Emiliania huxleyi enhances virulence of the bacterium Sulfitobacter D7, leading to algal bloom demise.