Author

D. Stegner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Nieswandt· 3 shared A. Ignatius· 1 shared A. Jeschke· 1 shared A. N. R. Weber· 1 shared C. Gross· 1 shared C. Kusch· 1 shared E. M. Soriano Jerez· 1 shared F. Herster· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersCell Biology

B. Nieswandt

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

G6b-B regulates an essential step in megakaryocyte maturation

I. C. Becker, Z. Nagy, G. Manukjan, M. Haffner-Luntzer, M. Englert, T. Heib, T. Voegtle, C. Gross, R. Bharti, S. Dietrich, K. Mott, J. Heck, A. Jeschke, T. Schinke, N. Schlegel, , B. Nieswandt

This study identifies G6b-B's critical role in early megakaryocyte differentiation by analyzing a mouse model with a mutation causing macrothrombocytopenia and myelofibrosis.

bioRxiv · Nov 11, 2021Cell Biology

Antibody-mediated depletion of human CLEC-2 in a novel humanised mouse model

H. C. Brown, S. Beck, S. Navarro, Y. Di, E. M. Soriano Jerez, J. Kaczmarzyk, S. G. Thomas, V. Mirakaj, S. P. Watson, B. Nieswandt, D. Stegner

This paper develops a humanised CLEC-2 mouse model and a monoclonal antibody to test anti-CLEC-2 therapeutics, showing transient thrombocytopenia without affecting haemostasis.

bioRxiv · Oct 3, 2021 · PreprintPhysiology

Mapping densely packed GPIIb/IIIa receptors in murine blood platelets with expansion microscopy

H. S. Heil, M. Aigner, S. Maier, P. Gupta, L. M. C. Evers, V. Goeb, C. Kusch, M. Meub, B. Nieswandt, D. Stegner, K. G. Heinze

This paper uses expansion microscopy to study GPIIb/IIIa receptor distribution in murine platelets, revealing clusters in resting platelets that persist through activation.

bioRxiv · Feb 16, 2021 · PreprintBiophysics

Platelet-neutrophil aggregates promote skin pathology in psoriasis

F. Herster, Z. Bittner, M. C. Codrea, N. Archer, M. Heister, M. W. Loeffler, S. Heumos, J. Wegner, R. Businger, M. Schindler, D. Stegner, K. Schaekel, S. Grabbe, K. Ghoreschi, L. Miller, A. N. R. Weber

This study identifies platelet-neutrophil aggregates as contributors to psoriasis skin pathology and disease severity.

bioRxiv · Jan 28, 2019 · PreprintImmunology