Author

C. M. Bradshaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Assay:flow cytometry· 1

Frequent Co-Authors

J. L. Uhrlaub· 2 shared J. Nikolich-Zugich· 2 shared M. Jergovic· 2 shared B. J. LaFleur· 1 shared C. P. Coplen· 1 shared D. Besselsen· 1 shared D. Bhattacharya· 1 shared J. Dudakov· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

J. L. Uhrlaub

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Author profile →

3 papers

Recent·Most cited

Characterization of low copy number human angiotensin-convertase 2 (hACE2)-transgenic mice as an improved model of SARS-CoV-2 infection

C. M. Bradshaw, T. Georgieva, T. N. Tankersley, T. Taylor-Doyle, L. Johnson, J. L. Uhrlaub, D. Besselsen, J. Z. Nikolich

This study develops low-copy hACE2 transgenic mice to better model SARS-CoV-2 infection, showing reduced mortality and viral spread compared to high-copy lines.

bioRxiv · Aug 31, 2023 · PreprintImmunology

Quantitative Restoration of Immune Defense in Old Animals Determined by Naive Antigen-Specific CD8 T cell Numbers

J. Uhrlaub, M. Jergovic, C. M. Bradshaw, S. Sonar, C. P. Coplen, J. Dudakov, K. O. Murray, M. C. Lanteri, M. P. Busch, M. R. M. van den Brink, J. Nikolich-Zugich

This study shows that increasing naive CD8 T cell numbers in old mice with IL-7C improves antigen-specific T cell numbers but not survival or effector immunity against WNV.

bioRxiv · Aug 9, 2021Immunology

Competent immune responses to SARS-CoV-2 variants in older adults following mRNA vaccination

M. Jergovic, J. L. Uhrlaub, M. Watanabe, C. M. Bradshaw, L. M. White, B. J. LaFleur, T. Edwards, R. Sprissler, M. Worobey, D. Bhattacharya, J. Nikolich-Zugich

This study shows older adults have robust cellular immunity and comparable neutralizing antibody responses to SARS-CoV-2 variants after mRNA vaccination.

bioRxiv · Jul 22, 2021 · PreprintImmunology