Author

C. Noecker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:metagenomics· 5 Approach:experimental assay· 4 Assay:metabolomics· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2

Frequent Co-Authors

J. E. Bisanz· 4 shared P. J. Turnbaugh· 4 shared E. Borenstein· 2 shared V. Upadhyay· 2 shared A. D. Patterson· 1 shared A. Eng· 1 shared A. Heinken· 1 shared A. R. Abate· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersMicrobiology

J. E. Bisanz

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Author profile →

6 papers

Recent·Most cited

Microbiome single cell atlases generated with a commercial instrument

X. Li, L. Xu, B. Demaree, C. Noecker, J. E. Bisanz, D. W. Weisgerber, C. Modavi, P. J. Turnbaugh, A. R. Abate

The paper introduces EASi-seq, a method for single-cell sequencing of microbes using a commercial platform, enabling detailed microbiome atlases and improved bioinformatic analysis.

bioRxiv · Aug 8, 2023 · PreprintBioengineering

Mild SARS-CoV-2 infection results in long-lasting microbiota instability

V. Upadhyay, R. Suryawanshi, P. Tasoff, M. McCavitt-Malvido, G. R. Kumar, V. Murray, C. Noecker, J. E. Bisanz, Y. Hswen, C. Ha, B. Sreekumar, I. P. Chen, S. V. Lynch, M. Ott, S. Lee, P. J. Turnbaugh

This study shows that mild SARS-CoV-2 infection causes long-term gut microbiota instability in both humans and mice, with Omicron variant also disrupting microbial communities despite causing milder symptoms.

mBio · Jun 9, 2023Peer-reviewedMicrobiology

Systems biology illuminates alternative metabolic niches in the human gut microbiome

C. Noecker, J. Sanchez, J. E. Bisanz, V. Escalante, M. Alexander, K. Trepka, A. Heinken, Y. Liu, D. Dodd, I. Thiele, B. DeFelice, P. J. Turnbaugh

This study identifies the metabolic niche of Eggerthella lenta in the human gut by combining experimental and computational approaches, revealing its use of acetate and arginine catabolism.

bioRxiv · Sep 19, 2022 · PreprintMicrobiology

MIMOSA2: A metabolic network-based tool for inferring mechanism-supported relationships in microbiome-metabolome data

C. Noecker, A. Eng, E. Borenstein

MIMOSA2 identifies microbiome-metabolite relationships by integrating genomic and metabolomic data with metabolic models.

bioRxiv · Sep 14, 2021Microbiology

Differences in the gut microbiomes of distinct ethnicities within the same geographic area are linked to host metabolic health

Q. Y. Ang, D. L. Alba, V. Upadhyay, J. E. Bisanz, J. Cai, H. L. Lee, E. Barajas, G. Wei, C. Noecker, A. D. Patterson, S. K. Koliwad, P. J. Turnbaugh

The paper compares gut microbiomes of East Asian and White individuals in the same geographic area, finding ethnic differences linked to metabolic health and independent of diet.

bioRxiv · Oct 23, 2020 · PreprintMicrobiology

Defining and Evaluating Microbial Contributions to Metabolite Variation in Microbiome-Metabolome Association Studies

C. Noecker, H.-C. Chiu, C. P. McNally, E. Borenstein

The paper evaluates the limitations of correlation-based analysis in microbiome-metabolome studies and introduces a framework to quantify microbial contributions to metabolite variation.

bioRxiv · Jan 11, 2019Microbiology