Author

G. R. Kumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

M. Ott· 5 shared R. Suryawanshi· 3 shared A. Ciling· 2 shared A. M. Syed· 2 shared I. P. Chen· 2 shared J. A. Doudna· 2 shared M. M. Khalid· 2 shared M. McCavitt-Malvido· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersMicrobiology

M. Ott

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variants

M. M. Khalid, I. Chen, F. S. Soveg, T. Y. Taha, T. Tabata, R. Suryawanshi, A. M. Syed, A. Ciling, M. McCavitt-Malvido, U. Schulze-Gahmen, J. Hayashi, I.-J. Kim, S. W. Fong, J. Batra, G. R. Kumar, , M. Ott

This study shows ORF8 suppresses viral particle production by interacting with Spike and causing Golgi fragmentation, supporting evolutionary pressure to delete ORF8 in SARS-CoV-2 variants.

bioRxiv · Mar 5, 2024 · PreprintMicrobiology

Mild SARS-CoV-2 infection results in long-lasting microbiota instability

V. Upadhyay, R. Suryawanshi, P. Tasoff, M. McCavitt-Malvido, G. R. Kumar, V. Murray, C. Noecker, J. E. Bisanz, Y. Hswen, C. Ha, B. Sreekumar, I. P. Chen, S. V. Lynch, M. Ott, S. Lee, P. J. Turnbaugh

This study shows that mild SARS-CoV-2 infection causes long-term gut microbiota instability in both humans and mice, with Omicron variant also disrupting microbial communities despite causing milder symptoms.

mBio · Jun 9, 2023Peer-reviewedMicrobiology

Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6

T. Y. Taha, I. P. Chen, J. M. Hayashi, T. Tabata, K. Walcott, G. R. Kimmerly, A. M. Syed, A. Ciling, R. K. Suryawanshi, H. S. Martin, B. H. Bach, C.-L. Tsou, M. Montano, M. M. Khalid, B. K. Sreekumar, , M. Ott

The paper introduces a plasmid-based method to assemble SARS-CoV-2 genomes and identifies NSP6 mutations as causing Omicron attenuation.

bioRxiv · Jan 31, 2023 · PreprintMicrobiology

A single-component luminescent biosensor for the SARS-CoV-2 spike protein

M. Ravalin, H. Roh, R. Suryawanshi, G. R. Kumar, J. E. Pak, M. Ott, A. Y. Ting

This paper develops a single-component luminescent biosensor for detecting SARS-CoV-2 spike protein using E. coli and S. cerevisiae, enabling detection with a cell phone camera.

bioRxiv · Jun 15, 2022Biochemistry

Novel RT-ddPCR assays for determining the transcriptional profile of SARS-CoV-2

S. Telwatte, N. Kumar, A. Vallejo-Gracia, G. R. Kumar, C. M. Lu, M. Ott, J. K. Wong, S. A. Yukl

This paper develops and validates quantitative RT-ddPCR assays to map SARS-CoV-2 transcription profiles, showing higher copy numbers for 3-end genomic targets in clinical samples.

bioRxiv · Jan 12, 2021 · PreprintMicrobiology