Author

C. O'Neill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Organism:human· 4 Assay:metagenomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Organism:rat· 2

Frequent Co-Authors

A. E. Hogan· 2 shared C. DeBarra· 2 shared D. O'Shea· 2 shared M. M. Pisarska· 2 shared N. A. Wood· 2 shared A. F. Plante· 1 shared A. I. Packman· 1 shared A. J. McBain· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

A. E. Hogan

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Spectral Characterization of a Blue Light-Emitting Micro-LED Platform and Microbial Chromophores for Therapeutic Applications in Skin Conditions

H. Serrage, C. A. Eling, P. U. Alves, A. J. McBain, C. O'Neill, N. Laurand

This paper characterizes blue light chromophores in skin commensals and presents a micro-LED platform for therapeutic applications in skin conditions.

bioRxiv · Mar 5, 2024 · PreprintMicrobiology

Regulation of Cardiomyocyte Adhesion and Mechanosignalling Through Distinct Nanoscale Behaviour of Integrin Ligands Mimicking Healthy or Fibrotic ECM

W. Hawkes, E. Marhuenda, P. M. Reynolds, C. O'Neill, P. Pandey, D. G. S. Wilson, M. Freeley, D. Huang, J. Hu, S. Gondarenko, J. Hone, N. Gadegaard, M. Palma, T. Iskratsch

This study investigates how integrin-ligand combinations affect cardiomyocyte adhesion, traction forces, and mechanosignalling in healthy and fibrotic ECM environments.

bioRxiv · Mar 13, 2022Cell Biology

Mucosal associated invariant T cells are altered in patients with Hidradenitis Suppurativa and contribute to the inflammatory milieu

C. Gallagher, J. MacMahon, C. O'Neill, F. C. Cassidy, H. Dunbar, C. DeBarra, C. Cadden, M. M. Pisarska, N. A. Wood, J. C. Masterson, E. N. McNamee, K. English, D. O'Shea, A.-M. Tobin, A. E. Hogan

This study shows MAIT cells are altered in Hidradenitis Suppurativa patients, with reduced frequencies and IL-17 bias, and highlights RORyt inhibition as a potential therapy.

bioRxiv · Jan 17, 2022Immunology

Human Mucosal Associated Invariant T cell proliferation is dependent on a MYC-SLC7A5-Glycolysis metabolic axis

N. Kedia-Mehta, M. M. Pisarska, C. Rollings, C. O'Neill, C. DeBarra, C. Foley, N. A. Wood, N. Wrigley-Kelly, N. Veerapen, G. E. Besra, R. Bergin, N. Jones, D. O'Shea, L. V. Sinclair, A. E. Hogan

This study identifies a MYC-SLC7A5-Glycolysis metabolic axis critical for MAIT cell proliferation, showing its impairment in obesity.

bioRxiv · Jan 17, 2022 · PreprintImmunology

Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson's disease

S. R. Stockdale, L. A. Draper, S. O'Donovan, W. Barton, O. O'Sullivan, L. A. Volpicelli-Daley, A. Sullivan, C. O'Neill, C. Hill

This study shows that alpha-synuclein treatment in rats alters their faecal virome, with changes persisting over five months and influenced by LPS.

bioRxiv · Mar 29, 2021 · PreprintMicrobiology

Ecological and genomic attributes of novel bacterial taxa that thrive in subsurface soil horizons

T. E. Brewer, E. L. Aronson, K. Arogyaswamy, S. A. Billings, J. K. Botthoff, A. N. Campbell, N. C. Dove, D. Fairbanks, R. E. Gallery, S. Hart, J. Kaye, G. M. King, G. Logan, K. A. Lohse, M. R. Maltz, , N. Fierer

The paper examines subsurface soil microbial communities across 20 U.S. profiles, finding decreased diversity and distinct taxa at depth, including the dominant Dormibacteraeota phylum, and identifies genomic traits enabling survival in oligotrophic conditions.

bioRxiv · May 24, 2019Microbiology

The power of model-to-crop translation illustrated by reducing seed loss from pod shatter in oilseed rape

P. Stephenson, N. Stacey, M. Brueser, N. Pullen, M. Ilyas, C. O'Neill, R. Wells, L. Ostergaard

The paper translates genetic insights from Arabidopsis to oilseed rape to reduce seed loss from pod shatter, increasing yield through gene mutation and software development.

bioRxiv · Apr 10, 2019Plant Biology