R. Wells

Chloride intracellular channel 4 (CLIC4) is a global regulator of type 1 interferon signaling in Systemic Sclerosis (SSc) epithelial cells

This study shows CLIC4 regulates type 1 interferon signaling in SSc epithelial cells and inhibiting it blocks IFN pathway activation.

Morphological Reprogramming of Primary Cilia Length Mitigates the Fibrotic Phenotype in fibroblasts across diverse fibrotic conditions

The paper shows that altering primary cilia length in fibroblasts can reduce fibrotic responses across different fibrotic conditions.

Wild bird mass mortalities in eastern Canada associated with the Highly Pathogenic Avian Influenza A(H5N1) virus, 2022

The paper estimates 40,966 wild bird mortalities in eastern Canada due to H5N1 avian influenza in 2022, highlighting potential population-level impacts on Northern Gannets and American Common Eiders.

Pathogen lifestyle determines host genetic signature of quantitative disease resistance in oilseed rape (Brassica napus)

The paper uses associative transcriptomics to identify host genetic loci associated with quantitative disease resistance in oilseed rape to four fungal pathogens, finding that resistance depends on pathogen lifestyle rather than broad-spectrum resistance.

Recognition of Necrosis and Ethylene-inducing like peptides confers disease resistance in Brassica napus and is modulated by BSK1 in Arabidopsis

This study identifies genomic regions and genes involved in NLP recognition in Brassica napus, showing their role in disease resistance and modulated by BSK1 in Arabidopsis.

Integrated Phenomics and Genomics reveals genetic loci associated with inflorescence growth in Brassica napus

The paper identifies genetic loci associated with inflorescence growth traits in Brassica napus using phenomics and genomics integration.

The Beta secretase BACE1 drives fibroblasts activation in Systemic Sclerosis through the APP/Beta-catenin/Notch signalling axis

This study shows BACE1 drives fibroblast activation in systemic sclerosis via the APP/Beta-catenin/Notch axis and identifies BACE1 as a potential therapeutic target.

Validation of a novel associative transcriptomics pipeline in Brassica oleracea: Identifying candidates for vernalisation response

This study validates a new associative transcriptomics pipeline in Brassica oleracea to identify vernalisation response candidates, finding miR172D and BoFLC.C2 as potential markers.

Comparative transcriptomics identifies differences in the regulation of the floral transition between Arabidopsis and Brassica rapa cultivars

This study compares gene expression dynamics during floral transition in Arabidopsis and Brassica rapa, revealing differences in regulatory networks and synchronization of gene expression.

A high-throughput delayed fluorescence method reveals underlying differences in the control of circadian rhythms in Triticum aestivum and Brassica napus

This study optimizes delayed fluorescence imaging for high-throughput circadian period measurement in wheat and oilseed rape, revealing species-specific differences in circadian robustness.

The power of model-to-crop translation illustrated by reducing seed loss from pod shatter in oilseed rape

The paper translates genetic insights from Arabidopsis to oilseed rape to reduce seed loss from pod shatter, increasing yield through gene mutation and software development.

Variation in expression of the HECT E3 ligase UPL3modulates LEC2 levels, gene expression, seed sizeand crop yields in Brassica napus.

The paper identifies variation in BnaUPL3.C03 expression that affects LEC2 levels, gene expression, seed size, and crop yields in Brassica napus.

Speed breeding in growth chambers and glasshouses for crop breeding and model plant research

This paper presents speed breeding protocols for various crops and model plants, detailing conditions and methods to accelerate generation advancement in growth chambers and glasshouses.

Regulatory divergence of flowering time genes in the allopolyploid Brassica napus

This study examines how duplicated flowering time genes are regulated in Brassica napus, finding diverged expression patterns and cis-regulatory differences that impact gene retention.