Author

P. Bousso

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. Proux· 2 shared E. Prina· 2 shared G. F. Spaeth· 2 shared H. Lecoeur· 2 shared H. Varet· 2 shared R. Legendre· 2 shared S. Zhang· 2 shared A. Ager· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. Proux

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Metabolically Primed Multipotent Hematopoietic Progenitors Fuel Innate Immunity

J. Cosgrove, A.-M. Lyne, I. Rodriguez, V. Cabeli, S. Tenreira-Bento, E. Tubeuf, E. Russo, F. Tabarin, Y. Belloucif, S. Maleki-Toyserkani, S. Reed, F. Monaco, A. Ager, C. Lobry, P. Bousso, , L. Perie

The paper identifies metabolic cues that guide innate immune cell development by showing how HSPC metabolism influences myeloid differentiation and immune cell production.

bioRxiv · Jan 24, 2023 · PreprintImmunology

Leishmania amazonensis controls macrophage-regulated cell death to establish chronic infection in vitro and in vivo

H. Lecoeur, S. Zhang, H. Varet, R. Legendre, C. Proux, C. Granjean, P. Bousso, E. Prina, G. F. Spaeth

This study shows Leishmania amazonensis suppresses macrophage-regulated cell death pathways to promote chronic infection in vitro and in vivo.

bioRxiv · Sep 14, 2022 · PreprintMicrobiology

The m6A reader IGF2BP2 directs immune-metabolic reprogramming in Leishmania amazonensis-infected macrophages

S. Zhang, H. Lecoeur, H. Varet, R. Legendre, N. Mahtal, C. Proux, N. Aulner, S. Short, C. Grandjean, P. Bousso, E. Prina, G. F. Spaeth

This study identifies IGF2BP2 as an m6A reader that stabilizes glycolytic transcripts in Leishmania-infected macrophages, promoting HIF-1-independent glycolysis and immune-metabolic reprogramming.

bioRxiv · Sep 8, 2022 · PreprintImmunology

A Multiscale Immuno-Oncology on-Chip System (MIOCS) establishes that collective T cell behaviors govern tumor regression

G. Ronteix, S. Jain, C. Angely, M. Cazaux, R. Khazen, P. Bousso, C. Baroud

The paper develops a microfluidic system to study T cell interactions with tumor spheroids, showing that collective T cell behaviors, not individual actions, drive tumor regression.

bioRxiv · Mar 23, 2021Biophysics

Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis

C. L. Grandjean, Z. Garcia, F. Lemaitre, B. Breart, P. Bousso

This study uses intravital imaging to show that antibody-dependent phagocytosis by bone marrow macrophages is the main mechanism of anti-CD20 therapy, but its efficiency is limited by time and spatial constraints.

bioRxiv · May 26, 2020Immunology

Macropinocytosis overcomes directional bias due to hydraulic resistance to enhance space exploration by dendritic cells

H. D. Moreau, C. Blanch-Mercader, R. Attia, Z. Alraies, M. Maurin, P. Bousso, J.-F. Joanny, R. Voituriez, M. Piel, A.-M. Lennon-Dumenil

This study shows that macropinocytosis enables immature dendritic cells to overcome hydraulic resistance, enhancing their space exploration and tissue-patrolling function, while mature dendritic cells are hindered by this resistance.

bioRxiv · Feb 27, 2018Cell Biology