C. Saito

Convolutional neural network model detected lasting behavioral changes in mouse with kanamycin-induced unilateral inner ear dysfunction

The paper uses a convolutional neural network to detect lasting behavioral changes in mice with unilateral inner ear dysfunction induced by kanamycin.

Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration

This study investigates the roles of WIPI proteins in autophagy and their implications in β-propeller associated neurodegeneration, finding that WIPI2 is essential for autophagy and that some BPAN-related mutations affect autophagic activity.

Experimental determination and mathematical modeling of standard shapes of forming autophagosomes

The paper determines the average shapes of forming autophagosomes using 3D electron microscopy and develops a model showing their morphology is determined by the ratio of rim size to surface area.

Cis-membrane association of human ATG8 proteins N-terminus mediates autophagy

This study shows that the N-termini of lipidated ATG8 proteins associate with membranes in cis, which is essential for autophagosome expansion and efficient p62 degradation.

NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and endosomal microferritinophagy

This study identifies NCOA4 as a driver of ferritin phase separation, enabling macroferritinophagy and endosomal microferritinophagy through multivalent interactions.