C. Shi

This study evaluates givinostat's efficacy in treating NASH by reducing inflammation and fibrosis in mouse models.

This study compares the effects of HSP25 vaccination and estrogen therapy on atherogenesis in post-menopausal mice, finding that both reduce plaque but through different mechanisms involving PCSK9 and LDLR.

This study reports the largest sequenced plant genome, Paris polyphylla var. yunnanensis, and identifies genes involved in polyphyllin biosynthesis.

The paper shows that HSP27 immune complexes reduce inflammation and cholesterol uptake by modulating TLR4 and scavenger receptors in macrophages.

The paper shows that HSP27 immune complexes increase LDLR expression, lowering plasma cholesterol and atherogenesis in ApoE-/- mice.

This study identifies a vertically transmitted core virome in Aedes albopictus mosquitoes across developmental stages and continents, and finds a novel virus related to Yongsan bunyavirus 1.

The paper develops a queuing model of stochastic transcription using non-exponential waiting-time distributions to better capture gene expression dynamics and shows that reduced waiting-time noise can increase mRNA noise.

This study evaluates how combining antivirals with different mechanisms delays resistance development in EV-A71 to pirodavir.

The paper reports the complete genome sequence of a novel BPV type 15 strain from a cow in southern Xinjiang and places it phylogenetically within the Xipapillomavirus genus.

This paper reports the crystal structure of a cardiac calsequestrin filament and identifies mutations that disrupt filament formation, linking them to arrhythmia.

This study shows mutant ACTB mRNA 3'UTR promotes HCC by interacting with miR-1 and miR-29a, leading to increased MET and MCL1 expression.

This paper examines how varying proportions of soft rock and sand affect soil organic carbon mineralization and particle composition, finding that ratios of 1:5 to 1:2 enhance organic carbon accumulation and stability.

The study examines EGFR exon19 mutation subtypes in non-small cell lung adenocarcinoma and finds that CSS mutations are associated with shorter progression-free survival compared to CD/CSS+SNV mutations.