Author

C.-F. Qin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

Q. Chen· 4 shared X.-F. Li· 4 shared Y.-Q. Deng· 4 shared Q. Ye· 3 shared X. Wang· 3 shared Y. Wang· 3 shared G. Yang· 2 shared H. Fan· 2 shared

Activity by Year

2020-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersMicrobiology

Q. Chen

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Competitive fitness and homologous recombination of SARS-CoV-2 variants of concern

C.-F. Qin, Q. Chen, Q. Si, H. Zhou, Y.-Q. Deng, P.-D. Shi, H. Zhao, X.-F. Li, X.-Y. Huang, Y. Wu, Y. Guo, G. Pei, Y. Wang, S.-Q. Sun, Z.-M. Du, , H. Fan

This study examines the competitive fitness and homologous recombination of SARS-CoV-2 variants in vitro, showing cell-specific fitness differences and recombination hotspots.

bioRxiv · Jul 26, 2023Microbiology

SARS-CoV-2 infection causes transient olfactory dysfunction in mice

C.-F. Qin, Q. Ye, J. Zhou, G. Yang, R.-T. Li, Q. He, Y. Zhang, S.-J. Wu, Q. Chen, J.-H. Shi, R.-R. Zhang, H.-M. Zhu, H.-Y. Qiu, T. Zhang, Y.-Q. Deng, , X. Yang

This study shows SARS-CoV-2 infection causes temporary olfactory dysfunction in mice by targeting olfactory epithelium cells and disrupting their structure and function.

bioRxiv · Nov 10, 2020 · PreprintMicrobiology

A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2

L. Zhang, L. Cao, X. Gao, B. Zheng, Y. Deng, J.-X. Li, R. Feng, Q. Bian, X.-L. Guo, N. Wang, H.-Y. Qiu, L. Wang, Z. Cui, Q. Ye, G. Chen, , F.-C. Zhu

A cocktail of neutralizing antibodies targeting SARS-CoV-2 spike protein's NTD and RBD, when used as immunogens in rabbits, elicited strong protective immune responses.

bioRxiv · Sep 23, 2020Microbiology

Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody

Z. Lv, Y.-Q. Deng, Q. Ye, L. Cao, C.-Y. Sun, C. Fan, W. Huang, S. Sun, Y. Sun, L. Zhu, Q. Chen, N. Wang, J. Nie, Z. Cui, D. Zhu, , X. Wang

A potent neutralizing antibody protected against SARS-CoV-2 in an hACE2 mouse model by blocking viral receptor interaction.

Science · Sep 18, 2020Peer-reviewedBiophysics

Modeling Human Peripheral Myelin Fully from Pluripotent Stem Cells and Immune-mediated Neuropathy In Vitro using ZIKA Virus

F. Mirakhori, Z. Xu, C.-F. Qin

This study generates a human peripheral myelination model from pluripotent stem cells and shows ZIKV induces GBS-like features in vitro.

bioRxiv · May 23, 2020 · PreprintCell Biology

Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy

H. Gu, Q. Chen, G. Yang, L. He, H. Fan, Y.-q. Deng, Y. Wang, Y. Teng, Z. Zhao, Y. Cui, Y. Li, X.-F. Li, J. Li, N. Zhang, X. Yang, , Y. Zhou

This paper develops a novel mouse model for SARS-CoV-2 infection and evaluates the protective efficacy of an RBD-based subunit vaccine.

bioRxiv · May 2, 2020 · PreprintMicrobiology