Author

C.-I. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

A. C. McQuattie-Pimentel· 2 shared A. V. Misharin· 2 shared C. J. Gottardi· 2 shared G. S. Budinger· 2 shared H. Perlman· 2 shared L. Sichizya· 2 shared N. Joshi· 2 shared P. A. Reyfman· 2 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. C. McQuattie-Pimentel

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Single-cell RNA-seq reveals spatially restricted multicellular fibrotic niches during lung fibrosis

N. Joshi, S. Watanabe, R. Verma, R. P. Jablonski, C.-I. Chen, P. Cheresh, P. A. Reyfman, A. C. McQuattie-Pimentel, L. Sichizya, A. S. Flozak, C. J. Gottardi, C. M. Cuda, H. Perlman, M. Jain, D. W. Kamp, , A. V. Misharin

The paper identifies monocyte-derived alveolar macrophages as causally linked to fibrosis in lung tissue through autocrine signaling and fibroblast activation.

European Respiratory Journal · Jan 1, 2020Peer-reviewedImmunology

The Aging Microenvironment Shapes Alveolar Macrophage Identity in Aging

A. C. McQuattie-Pimentel, Z. Ren, N. Joshi, S. Watanabe, T. Stoeger, M. Chi, Z. Lu, L. Sichizya, R. Piseaux, C.-I. Chen, S. Soberanes, P. A. Reyfman, J. M. Walter, K. R. Anekalla, J. M. Davis, , G. S. Budinger

This study shows that the aging lung microenvironment shapes alveolar macrophage identity, influencing their phenotype during aging and after injury.

bioRxiv · Jul 29, 2019 · PreprintImmunology