Author

P. A. Reyfman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. V. Misharin· 4 shared G. S. Budinger· 4 shared A. C. McQuattie-Pimentel· 3 shared H. Abdala-Valencia· 3 shared L. Sichizya· 3 shared N. Joshi· 3 shared S. Watanabe· 3 shared C. E. Runyan· 2 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

A. V. Misharin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Influenza-induced activation of recruited alveolar macrophages during the early inflammatory phase drives lung injury and lethality

C. M. Koch, K. Anekalla, Y.-S. Hu, J. M. Davis, M. Ciesielski, G. Gadhvi, S.-Y. Chen, M. Turner, Y. Cheng, B. M. Coates, H. Abdala-Valencia, P. A. Reyfman, A. V. Misharin, G. S. Budinger, D. R. Winter, K. M. Ridge

This study identifies vimentin's role in driving pro-inflammatory responses in alveolar macrophages during influenza infection, linking it to lung injury and mortality.

bioRxiv · Jun 8, 2020 · PreprintImmunology

Resetting proteostasis with ISRIB prevents pulmonary fibrosis

S. Watanabe, N. S. Markov, Z. Lu, R. Piseaux Aillon, S. Soberanes, C. E. Runyan, Z. Ren, R. A. Grant, M. Maciel, H. Abdala-Valencia, Y. Politanska, K. Nam, L. Sichizya, H. G. Kihshen, N. Joshi, , A. V. Misharin

ISRIB reduces pulmonary fibrosis severity in young and old mice by modulating stress response signaling in alveolar epithelial cells.

bioRxiv · Feb 26, 2020 · PreprintImmunology

Single-cell RNA-seq reveals spatially restricted multicellular fibrotic niches during lung fibrosis

N. Joshi, S. Watanabe, R. Verma, R. P. Jablonski, C.-I. Chen, P. Cheresh, P. A. Reyfman, A. C. McQuattie-Pimentel, L. Sichizya, A. S. Flozak, C. J. Gottardi, C. M. Cuda, H. Perlman, M. Jain, D. W. Kamp, , A. V. Misharin

The paper identifies monocyte-derived alveolar macrophages as causally linked to fibrosis in lung tissue through autocrine signaling and fibroblast activation.

European Respiratory Journal · Jan 1, 2020Peer-reviewedImmunology

The Aging Microenvironment Shapes Alveolar Macrophage Identity in Aging

A. C. McQuattie-Pimentel, Z. Ren, N. Joshi, S. Watanabe, T. Stoeger, M. Chi, Z. Lu, L. Sichizya, R. Piseaux, C.-I. Chen, S. Soberanes, P. A. Reyfman, J. M. Walter, K. R. Anekalla, J. M. Davis, , G. S. Budinger

This study shows that the aging lung microenvironment shapes alveolar macrophage identity, influencing their phenotype during aging and after injury.

bioRxiv · Jul 29, 2019 · PreprintImmunology