Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
Y. J. Wang, A. Yemelyanov, C. D. Go, S. Kim, J. M. Quinn, A. S. Flozak, P. M. Le, S. Liang, A.-C. Gingras, M. Ikura, N. Ishiyama, C. J. Gottardi
This study identifies α-catenin mechanosensitivity as a driver of cytokinesis failure through sequestration of LZTS2, linking it to polyploidization and retinal dystrophy.
Journal of Cell Biology · Jan 9, 2025Peer-reviewedCell Biology
J. M. Quinn, Y. Wang, M. N. Wood, A. S. Flozak, P. M. Le, A. Yemelyanov, P. W. Oakes, C. J. Gottardi
This study compares how mutations in α-catenin's M-domain and FABD affect epithelial strength and migration by analyzing cell behavior and protein interactions.
bioRxiv · Feb 1, 2023Cell Biology
A. Weng, E. E. Rabin, A. S. Flozak, R. P. Aillon, S. E. Chiarella, C. J. Gottardi
The paper identifies alpha-T-catenin expression in Schwann cell adherens junctions of peripheral nerves and links CTNNA3 to neuroglial functions, potentially explaining its association with non-cardiac diseases.
bioRxiv · Sep 15, 2022Cell Biology
A. Weng, M. Maciel-Herrerias, S. J. Watanabe, A. S. Flozak, L. Welch, R. P. Aillon, R. Grant, S. Han, L. Dada, M. HInchcliff, A. Misharin, G. S. Budinger, C. J. Gottardi
This study shows lung injury induces alveolar type 2 cell hypertrophy and polyploidy, which can be reduced by inhibiting the integrated stress response.
American Journal of Respiratory Cell and Molecular Biology · May 1, 2022Peer-reviewedCell Biology
L. A. Dada, L. C. Welch, N. D. Magnani, Z. Ren, P. L. Brazee, D. Celli, A. S. Flozak, A. Weng, M. Maciel-Herrerias, V. Kryvenko, I. Vadasz, C. E. Runyan, H. Abdala-Valencia, M. Shigemura, S. M. Casalino-Matsuda, , J. I. Sznajder
This study shows hypercapnia inhibits β-catenin signaling in alveolar type 2 cells by altering Wnt production from fibroblasts, impairing lung repair after injury.
bioRxiv · Jan 12, 2022 · PreprintCell Biology
R. A. Grant, L. Morales-Nebreda, N. S. Markov, S. Swaminathan, E. R. Guzman, D. A. Abbott, H. K. Donnelly, A. Donayre, I. A. Goldberg, Z. M. Klug, N. Borkowski, Z. Lu, H. Kihshen, Y. Politanska, L. Sichizya, , The NU SCRIPT Study Investigators
The paper identifies a positive feedback loop between SARS-CoV-2-infected alveolar macrophages and T cells in severe COVID-19 patients, driving persistent alveolitis.
Nature · Jan 11, 2021Peer-reviewedImmunology
N. Joshi, S. Watanabe, R. Verma, R. P. Jablonski, C.-I. Chen, P. Cheresh, P. A. Reyfman, A. C. McQuattie-Pimentel, L. Sichizya, A. S. Flozak, C. J. Gottardi, C. M. Cuda, H. Perlman, M. Jain, D. W. Kamp, , A. V. Misharin
The paper identifies monocyte-derived alveolar macrophages as causally linked to fibrosis in lung tissue through autocrine signaling and fibroblast activation.
European Respiratory Journal · Jan 1, 2020Peer-reviewedImmunology
A. C. McQuattie-Pimentel, Z. Ren, N. Joshi, S. Watanabe, T. Stoeger, M. Chi, Z. Lu, L. Sichizya, R. Piseaux, C.-I. Chen, S. Soberanes, P. A. Reyfman, J. M. Walter, K. R. Anekalla, J. M. Davis, , G. S. Budinger
This study shows that the aging lung microenvironment shapes alveolar macrophage identity, influencing their phenotype during aging and after injury.
bioRxiv · Jul 29, 2019 · PreprintImmunology