Author

C. Chou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

E. Stamatiades· 2 shared K. Capistrano· 2 shared M. Do· 2 shared M. Li· 2 shared A. Hakimi· 1 shared A. Levine· 1 shared A. P. Rossi· 1 shared A. Perez-Posada· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

E. Stamatiades

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Author profile →

4 papers

Recent·Most cited

Chromosome-level genome assemblies of two hemichordates provide new insights into deuterostome origin and chromosome evolution

C.-Y. Lin, F. Marletaz, A. Perez-Posada, P. M. Martinez Garcia, S. Schloissnig, P. Peluso, G. T. Conception, P. Bump, Y.-C. Chen, C. Chou, C.-Y. Lin, T.-P. Fan, C.-T. Tsai, J. L. Gomez Skarmeta, J. J. Tena, , Y.-H. Su

This study presents chromosome-level genome assemblies of two hemichordates to infer deuterostome ancestral chromosomal architecture and lineage-specific modifications.

bioRxiv · Nov 1, 2023Evolutionary Biology

Glycolysis Fuels Phosphoinositide 3-Kinase Signaling to Bolster T Cell Immunity

K. Xu, N. Yin, M. Peng, E. Stamatiades, A. Shyu, P. Li, X. Zhang, M. Do, Z. Wang, K. Capistrano, C. Chou, A. Levine, A. Rudensky, M. Li

This study shows that glycolysis fuels PI3K signaling in CD8+ T cells, linking metabolic reprogramming to T cell immunity and suggesting therapeutic targets for infectious diseases and cancer.

Science · Jan 22, 2021Peer-reviewedImmunology

TGFβ Suppresses Type 2 Immunity to Cancer

M. Liu, F. Kuo, K. Capistrano, D. Kang, B. Nixon, W. Shi, C. Chou, M. Do, S. Li, E. Stamatiades, Y. Chen, J. Hsieh, A. Hakimi, I. Taniuchi, T. Chan, M. Li

This study shows that blocking TGFβ signaling in CD4+ T cells enhances type 2 immunity, promoting tumor healing and halting cancer progression through IL-4-mediated vasculature repair.

bioRxiv · Mar 4, 2020 · PreprintImmunology

Detecting Direct Oral Anticoagulants in Trauma Patients using Liquid Chromatography-Mass Spectrometry: a Novel Approach to Medication Reconciliation

S. Jayaraman, J. H. DeAntonio, S. W. Leichtle, J. Han, L. Liebrecht, D. Contaifer, C. Young, C. Chou, J. Staschen, D. Doan, N. G. Kumar, L. Wolfe, T. Nguyen, G. Chenault, R. J. Anand, , D. S. Wijesinghe

This paper develops an LCMS-based assay to detect DOACs in trauma patients, achieving high accuracy and identifying potential medication reconciliation issues.

bioRxiv · May 27, 2019Pharmacology & Toxicology