Author

Yachuan Yu

Cancer Research UK Scotland Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 4

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Julia B. CorderoiD· 4 shared Jessica PerochoniD· 3 shared André B. Medina· 2 shared Yuanliangzi TianiD· 2 shared Alexander R Cameron· 1 shared Alisson M. GontijoiD· 1 shared André Barros-CarvalhoiD· 1 shared Anna M Ochocka-Fox· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersDevelopmental Biology

Julia B. CorderoORCID

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4 papers

Recent·Most cited

Biomechanical Compartmentalisation Influences Angiogenesis and Stem Cell Proliferation in the Regenerating Intestine via Vascular Piezo.

Jade A. Phillips, Jessica Perochon, Cai T. Johnson, Matthew Walker, Colin Nixon, Mark M. Hughes, André Barros-Carvalho, Yachuan Yu, Louise E. Mitchell, Karen Blyth, Massimo Vassalli, Julia B. Cordero

This study identifies biomechanical compartmentalization in the regenerating intestine and shows vascular Piezo1 influences angiogenesis and stem cell proliferation across species.

bioRxiv · Apr 16, 2025 · PreprintDevelopmental Biology

Non-gonadal PIWI protein, Aubergine, regulates regenerative stem cell proliferation and tumourigenesis in the Drosophila adult intestine.

Karen Bellec, Lynsey Rose Carroll, Kathryn A.F. Pennel, Yuanliangzi Tian, Yachuan Yu, Aslihan Bastem Akan, Caroline V Billard, Nora Doleschall, Alexander R Cameron, Fabiana Herédia, Alisson M. Gontijo, Anna M Ochocka-Fox, James P Blackmur, Farhat V N Din, Malcolm G Dunlop, , Julia B. Cordero

This study shows Aubergine regulates ISC proliferation and tumourigenesis in Drosophila intestine through protein synthesis, independent of its piRNA function.

bioRxiv · Nov 4, 2024 · PreprintDevelopmental Biology

Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila.

André B. Medina, Jessica Perochon, Cai Johnson, Sofia Polcowñuk, Yuanliangzi Tian, Yachuan Yu, Julia B. Cordero

The paper identifies a novel signaling network involving enteroendocrine cells, neurons, and vascular structures that regulates stem cell proliferation during intestinal regeneration in Drosophila.

bioRxiv · Sep 10, 2024 · PreprintDevelopmental Biology

Dynamic adult tracheal plasticity drives stem cell adaptation to changes in intestinal homeostasis.

Jessica Perochon, Yachuan Yu, Gabriel Aughey, André B. Medina, Tony D. Southall, Julia B. Cordero

This study identifies a novel crosstalk between Drosophila intestinal stem cells and the tracheal system, showing that reactive oxygen species drive tracheal plasticity to support intestinal regeneration.

Nature Cell Biology · May 1, 2021Peer-reviewedDevelopmental Biology