Author

Carrie Ng

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1

Frequent Co-Authors

Casey A. MaguireiD· 2 shared Demitri de la Cruz· 2 shared Miguel C. SantoscoyiD· 2 shared Paula EspinozaiD· 2 shared Ana Griciuc· 1 shared Angela M. CacaceiD· 1 shared Chicheng SuniD· 1 shared Christian E. BadriD· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBioengineering

Casey A. MaguireORCID

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3 papers

Recent·Most cited

Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice

Miguel C. Santoscoy, Paula Espinoza, Killian S. Hanlon, Luna Yang, Lisa Nieland, Carrie Ng, Christian E. Badr, Suzanne E. Hickman, Demitri de la Cruz, Ana Griciuc, Joseph B. El Khoury, Rachel E. Bennett, Shiqian Shen, Casey A. Maguire

The paper identifies an AAV capsid, MC5, that efficiently and specifically transduces microglia via direct and intracerebroventricular injection in mice.

bioRxiv · Sep 25, 2024 · PreprintBioengineering

Metabolic engineering improves transduction efficiency and downstream vector isolation by altering the lipid composition of extracellular vesicle-enclosed AAV.

Paula Espinoza, Ming Liang Cheng, Carrie Ng, Demitri de la Cruz, Elizabeth D Wasson, Deirdre M. McCarthy, Pradeep G. Bhide, Casey A. Maguire, Miguel C. Santoscoy

Metabolic Engineering · Aug 19, 2024Peer-reviewedBioengineering

Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons

John D. Graef, Hao Wu, Carrie Ng, Chicheng Sun, Vivian Villegas, Deena Qadir, Kimberly Jesseman, Stephen T. Warren, Rudolf Jaenisch, Angela M. Cacace, Owen B. Wallace

The paper shows that restoring over 5% FMRP expression or 20% FMRP-positive neurons in FXS neurons normalizes hyperactivity.

European Journal of Neuroscience · Dec 26, 2019Peer-reviewedNeuroscience