Author

Casey O. Swoboda

Cincinnati Children's Hospital Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2

Frequent Co-Authors

Douglas P. MillayiD· 4 shared Cristofer CalvoiD· 3 shared Matthew T. WeirauchiD· 3 shared Carmy R. ForneyiD· 2 shared Fabián MontecinoiD· 2 shared Leah Claire KottyaniD· 2 shared Lucinda P. LawsoniD· 2 shared Vikram PrasadiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCell Biology

Douglas P. MillayORCID

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Author profile →

5 papers

Recent·Most cited

Single nucleus RNA sequencing of juvenile dermatomyositis skeletal muscle identifies altered angiogenic signaling

Casey O. Swoboda, Carmy R. Forney, Cristofer Calvo, Lucinda P. Lawson, Hilal Cevik, Kairavee Thakkar, Caitlin Treuting, Stephen N. Waggoner, Cheryl B. Bayart, Meredith Posner Schuh, A. Zygmunt, Sheila T. Angeles‐Han, Alexei A. Grom, Grant S. Schulert, Nathan Salomonis, , Shannon K. O’Connor

This study uses single nucleus RNA sequencing to identify altered angiogenic signaling in JDM muscle, highlighting vascular and IFN pathways.

bioRxiv · May 7, 2026 · PreprintGenomics

Enhanced EBNA2-dependent activity in EBV-transformed B cells from patients with multiple sclerosis

Marissa Granitto, Ellie Kim, Carmy R. Forney, Cailing Yin, Arame A. Diouf, Andrew VonHandorf, Phillip J. Dexheimer, Sreeja Parameswaran, Xiaoting Chen, Omer A. Donmez, Hope Rowden, Casey O. Swoboda, Molly Shook, Katelyn A. Dunn, Hania Kébir, , Matthew T. Weirauch

This study shows that EBNA2 activity is increased in MS patients, altering gene expression and chromatin accessibility in EBV-transformed B cells.

medRxiv · Mar 9, 2026 · PreprintGenetic & Genomic Medicine

mRNA transcription in skeletal muscle drives growth and determines nuclear accretion

Fabián Montecino, Cristofer Calvo, Casey O. Swoboda, Alena S Bruening, A. Cramer, Xin Lin, Jennifer L. Martin, Ramzi J. Khairallah, Yarui Diao, Vikram Prasad, Douglas P. Millay

The paper shows that increasing RNA Polymerase II levels enhances mRNA content and drives myofiber growth without needing additional nuclei.

bioRxiv · Dec 29, 2025 · PreprintCell Biology

The multimodal transcriptional response of denervated skeletal muscle involves alterations in cholesterol homeostasis impacting muscle size

Cristofer Calvo, Casey O. Swoboda, Fabián Montecino, Siddhant Nagar, Michael J. Petrany, Chengyi Sun, Hima Bindu Durumutla, Mattia Quattrocelli, Douglas P. Millay

This study identifies a multimodal transcriptional response in denervated skeletal muscle, revealing altered cholesterol homeostasis and its impact on myofiber size.

Proceedings of the National Academy of Sciences · Sep 23, 2025Peer-reviewedCell Biology

Cardiomyocyte-expressed TGFβ signals to fibroblasts to program early heart maturation and adult myocyte identity

Rachel A Minerath, Rajesh K. Kasam, Casey O. Swoboda, Vikram Prasad, Kelly M. Grimes, N. Scott Blair, Hadi Khalil, Christina M. Alfieri, Logan Eads, Anthony J. Saviola, Mohamad Azhar, Lianjie Miao, Mingfu Wu, Michelle D. Tallquist, Kirk Charles Hansen, , Jeffery D. Molkentin

This study shows that TGFβ from cardiomyocytes programs fibroblast development and ECM environment to support cardiomyocyte maturation in the developing heart.

bioRxiv · Sep 22, 2025 · PreprintDevelopmental Biology