Exponential increase in QTL detection with increased sample size.
Apurva S. Chitre, Oksana Polesskaya, Daniel B. Munro, Riyan Cheng, Pejman Mohammadi, Katie Holl, Jianjun Gao, Hannah V. Bimschleger, Angel Garcia Martinez, Anthony M. George, Alexander F. Gileta, Aidan P. Horvath, Alesa Hughson, Keita Ishiwari, Christopher P. King, , Abraham A. Palmer
The paper simulates GWAS in rats to show that larger sample sizes lead to an exponential increase in the number of significant loci detected.
bioRxiv · Jan 27, 2023 · PreprintGenetics