Author

Celia da Cunha

University of California, Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andrea J. TenneriD· 4 shared Frank M. LaFerlaiD· 4 shared Grant R. MacGregoriD· 4 shared Jonathan C. Neumann· 4 shared Kim N. GreeniD· 4 shared Kristine M. TraniD· 4 shared Shimako KawauchiiD· 4 shared Ali MortazaviiD· 3 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Andrea J. TennerORCID

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4 papers

Recent·Most cited

APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology

Kristine M. Tran, Nellie E. Kwang, Claire Ann Butler, Ángela Gómez-Arboledas, Shimako Kawauchi, Cassandra Mar, Donna Chao, Rocio A. Barahona, Celia Da Cunha, Kate Inman Tsourmas, Zechuan Shi, Shuling Wang, Sherilyn Collins, Amber Walker, Kai‐Xuan Shi, , Kim N. Green

The paper investigates how the APOE Christchurch variant affects microglial responses to amyloid and tau pathology in mouse models, finding it enhances plaque-related responses but suppresses tau-related inflammation.

Molecular Neurodegeneration · Jan 22, 2025Peer-reviewedNeuroscience

A Trem2*R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques

Kristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia da Cunha, Jimmy Phan, Shuling Wang, Sherilyn Collins, Amber Walker, Kai‐Xuan Shi, Jonathan C. Neumann, , Kim N. Green

Molecular Neurodegeneration · Feb 17, 2023Peer-reviewedNeuroscience

Systematic phenotyping and characterization of the 3xTg-AD mouse model of Alzheimer's Disease

Dominic I. Javonillo, Kristine M. Tran, Jimmy Phan, Edna E. Hingco, Enikö A. Kramár, Celia da Cunha, Stefânia Forner, Shimako Kawauchi, Giedre Milinkeviciute, Ángela Gómez-Arboledas, Jonathan C. Neumann, Crystal E. Banh, Michelle Dieu Thao Huynh, Dina P. Matheos, Narges Rezaie, , Frank M. LaFerla

This paper characterizes the 3xTg-AD mouse model of Alzheimer's Disease across its lifespan and compares it with the 5xFAD model to assess pathology and model drift.

Frontiers in Neuroscience · Jan 24, 2022Peer-reviewedNeuroscience

Systematic Phenotyping and Characterization of the 5xFAD mouse model of Alzheimer's Disease

Stefânia Forner, Shimako Kawauchi, Gabriela Balderrama-Gutierrez, Enikö A. Kramár, Dina P. Matheos, Jimmy Phan, Dominic I. Javonillo, Kristine M. Tran, Edna E. Hingco, Celia da Cunha, Narges Rezaie, Joshua A. Alcantara, David Baglietto‐Vargas, Camden S. Jansen, Jonathan C. Neumann, , Kim N. Green

The paper performs a comprehensive phenotypic analysis of the 5xFAD mouse model across its lifespan, identifying novel age-related pathological features.

Scientific Data · Oct 15, 2021Peer-reviewedNeuroscience