Author

Emily Overington

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adam Davison· 1 shared Ahmed ShaabaniD· 1 shared Charity N. Bhebhe· 1 shared Christopher A. Smith· 1 shared Constanza AlcainoiD· 1 shared Cordelia ImigiD· 1 shared David Colin BulmeriD· 1 shared Emily L. MiedzybrodzkaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Adam Davison

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Protease-activated receptor 1-mediated matrix metalloprotease signalling in sensory neurons

Katie J Williams, Giulia Galimberti, James P. Higham, Emily Overington, Charity N. Bhebhe, Tim Raine, Paola Sacerdote, David Colin Bulmer

This study identifies MMP3, MMP8, and MMP9 as inducers of Ca2+ release in DRG neurons via PAR1 and PLC activation, revealing a novel role for MMP signaling in sensory neurons during inflammation.

bioRxiv · Aug 20, 2025 · PreprintNeuroscience

Mechanisms of Activation and Serotonin release from Human Enterochromaffin Cells

Constanza Alcaino, Nunzio Guccio, Emily L. Miedzybrodzka, Jaden R Quale, Tianyi Lu, Adam Davison, Christopher A. Smith, Emily Overington, Marta Santos-Hernández, Mae Tabbada, Megan Hodge, Rula Bany Bakar, Richard G. Kay, Ahmed Shaaban, Cordelia Imig, , Fiona Mary Gribble

This study investigates mechanisms of serotonin release from human enterochromaffin cells using organoids and functional assays, identifying key receptors and signaling pathways involved.

Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2025Peer-reviewedCell Biology