Author

Charlie Haslam

GlaxoSmithKline (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Chloe L. TayleriD· 2 shared Denise F. Vlachou· 2 shared Evan Rosa-Roseberry· 2 shared Lee M. BootyiD· 2 shared Leonie MülleriD· 2 shared Rachel E. HeapiD· 2 shared Serena BatemaniD· 2 shared Aikaterini GeladakiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Chloe L. TaylerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-throughput platforms for genetic perturbation screening using CRISPR/Cas9 in human iPSC-derived macrophages for drug discovery

Matteo Martufi, Eleni Karagianni, Tasos Papanikos, Tim G. Ashlin, Aikaterini Geladaki, Benedetta Carbone, Katja S. Remlinger, Andres Quintero Moreno, William G. Pembroke, Charlie Haslam, Nico Zinn, Denise F. Vlachou, Margarida Almeida, Dimitrios Tsaousis, Stephan Gade, , Lisa Mohamet

The paper establishes a CRISPR/Cas9 screening platform in hiPSC-derived macrophages to identify genetic targets influencing inflammatory responses and functional phenotypes.

bioRxiv · Sep 14, 2026 · PreprintImmunology

dia-PASEF Enables Rapid Profiling of the Human Secretome for Deeper Insights into Cellular Dynamics and Inflammatory Mechanisms

Chloe L. Tayler, Serena Bateman, Charlie Haslam, Leonie Müller, Kerena Norris, Evan Rosa-Roseberry, Stan Martens, Jonathan Yu, Eleanor R. Dickinson, Lee M. Booty, Rebecca Beveridge, Nicholas J. W. Rattray, Rachel E. Heap

The paper introduces dia-PASEF, a mass spectrometry workflow for rapid secretome profiling, revealing novel inflammatory responses and dynamic secretion patterns in macrophages.

Molecular & Cellular Proteomics · May 28, 2026Peer-reviewedImmunology

MALDI-TOF mass spectrometry and proteomics as phenotypic screening tools for anti-inflammatory drugs

Leonie Müller, Serena Bateman, Charlie Haslam, Thomas K. Dawson, Denise F. Vlachou, Evan Rosa-Roseberry, Lee M. Booty, Chloe L. Tayler, Andrew Michael Frey, Roland S. Annan, Melanie V. Leveridge, María Emilia Dueñas, Rachel E. Heap, Matthias Trost

This study evaluates two mass spectrometry-based phenotypic screening approaches for identifying anti-inflammatory compounds in macrophages and compares them to cytokine profiling.

bioRxiv · Dec 3, 2025 · PreprintBiochemistry