Author

Matteo Martufi

GlaxoSmithKline (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Joanna C. BettsiD· 2 shared Klio MaratouiD· 2 shared Radu RapiteanuiD· 2 shared Aikaterini GeladakiiD· 1 shared Alessandro Di Tullio· 1 shared Andres Quintero Moreno· 1 shared Andy D. BlanchardiD· 1 shared Benedetta Carbone· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Joanna C. BettsORCID

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Author profile →

4 papers

Recent·Most cited

High-throughput platforms for genetic perturbation screening using CRISPR/Cas9 in human iPSC-derived macrophages for drug discovery

Matteo Martufi, Eleni Karagianni, Tasos Papanikos, Tim G. Ashlin, Aikaterini Geladaki, Benedetta Carbone, Katja S. Remlinger, Andres Quintero Moreno, William G. Pembroke, Charlie Haslam, Nico Zinn, Denise F. Vlachou, Margarida Almeida, Dimitrios Tsaousis, Stephan Gade, , Lisa Mohamet

The paper establishes a CRISPR/Cas9 screening platform in hiPSC-derived macrophages to identify genetic targets influencing inflammatory responses and functional phenotypes.

bioRxiv · Sep 14, 2026 · PreprintImmunology

A signalling axis involving CNOT3, Aurora B and ERK promotes differentiation and survival of mesendodermal progenitor cells

Moumita Sarkar, Matteo Martufi, Monica Roman-Trufero, Yi-Fang Wang, Chad Whilding, Dirk Dormann, Pierangela Sabbattini, Niall Dillon

Molecular Biology of the Cell · Oct 6, 2021Peer-reviewedDevelopmental Biology

Highly efficient genome editing in primary bronchial epithelial cells establishes FOXJ1 as essential for ciliation in human airways

Radu Rapiteanu, Tina Karagyozova, Natalie Zimmermann, Kuljit Singh, Gareth J. Wayne, Matteo Martufi, Nikolai Nikolaevich Belyaev, Edith M. Hessel, David Michalovich, Ricardo Macarrón, Wendy C. Rowan, William J. Cairns, Jan Roger, Joanna C. Betts, Sören Beinke, Klio Maratou

This study uses genome editing to show that FOXJ1 is essential for ciliation in human airway epithelial cells.

European Respiratory Journal · Feb 14, 2020Peer-reviewedMolecular Biology

Single step, high efficiency CRISPR-Cas9 genome editing in primary human disease-derived fibroblasts

Matteo Martufi, Robert B. Good, Radu Rapiteanu, Tobias Schmidt, Eleni Patili, Ketil Tvermosegaard, Maria I. New, Carmel B. Nanthakumar, Joanna C. Betts, Andy D. Blanchard, Klio Maratou

This study develops a single-step CRISPR-Cas9 method for high-efficiency genome editing in primary human fibroblasts without antibiotic selection or clonal expansion, achieving >90% knockout efficiency.

The CRISPR Journal · Feb 1, 2019Peer-reviewedMolecular Biology