Chih-Cheng Yang

Automation workflow for high-throughput arrayed plasmid DNA preparation and quantification.

The paper describes an automated workflow for high-throughput plasmid DNA preparation and quantification using a robotic workstation, achieving high yields and quality with minimal human intervention.

Automation of high-throughput workflow for arrayed CRISPR activation library screening

This paper develops an automated high-throughput workflow for arrayed CRISPRa screening, demonstrating its effectiveness in identifying growth reduction phenotypes in HEK293 cells.

Automation of high-throughput arrayed lentivirus production and titration

This paper develops an automated workflow for high-throughput lentivirus production and titration, achieving high reproducibility and efficiency in generating CRISPR libraries.

Automation of high-throughput arrayed mammalian cell line cultivation

This paper automates high-throughput mammalian cell culture workflows using an integrated workstation and software, enabling efficient clonal line establishment.

SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells

The 73-amino-acid SARS-CoV-2 membrane-associated protein ORF9c suppresses interferon, antigen presentation, and complement pathways while inducing IL-6 signaling in lung epithelial cells, an effect blunted by proteasome or VCP inhibition.