Author

Christine M. Wright

University of Alabama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:DNA methylation· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Azait ImtiaziD· 3 shared Bo-Ruei CheniD· 3 shared Rafael Contreras-GalindoiD· 3 shared Wioletta CzajaiD· 3 shared Mohammad WaseemiD· 2 shared Aaiyas MujawariD· 1 shared Anindya DuttaiD· 1 shared Arko SeniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersGenetics

Azait ImtiazORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Centromeric α-satellite DNA is a hotspot of genotoxic damage, incomplete repair, and cytoplasmic mislocalization

Azait Imtiaz, Mohammad Waseem, Hudson O'Neill, Christine M. Wright, Bo-Ruei Chen, Wioletta Czaja, Rafael Contreras-Galindo

The paper shows that centromeric α-satellite DNA is prone to genotoxic damage, incomplete repair, and cytoplasmic mislocalization, leading to chromosome instability and chromatin antigen exposure.

bioRxiv · May 5, 2026 · PreprintGenetics

Chromatin regulator HELLS mediates SSB repair and responses to DNA alkylation damage.

Joyous T. Joseph, Christine M. Wright, Estanislao Peixoto, Etsuko Shibata, Asad Ullah Khan, Yong Li, Jason Romero Neidigk, Bo-Ruei Chen, Saba Tufail, Aaiyas Mujawar, Olivia Decker, Krishna Reethika Kadali, Azait Imtiaz, Brianna A Jones, Yanfeng Zhang, , Wioletta Czaja

This study identifies HELLS as a regulator of SSB repair and DNA alkylation damage response, showing its synthetic lethality with HRD in cancer.

Nucleic Acids Research · Oct 21, 2025Peer-reviewedMolecular Biology

Bleomycin induces active-centromere damage and cytoplasmic mislocalization of centromeric chromatin in fibroblasts

Azait Imtiaz, Mohammad Waseem, Hudson O’Neill, Christine M. Wright, Bo-Ruei Chen, Wioletta Czaja, Rafael Contreras-Galindo

This study shows bleomycin causes centromere damage and chromatin mislocalization in fibroblasts, linking it to systemic sclerosis features.

bioRxiv · Aug 22, 2025 · PreprintGenetics