Yong Li

This paper shows that NX-5948, a BTK degrader, reduces thrombosis without affecting haemostasis by selectively degrading platelet BTK.

This study identifies HELLS as a regulator of SSB repair and DNA alkylation damage response, showing its synthetic lethality with HRD in cancer.

The paper introduces a cell-based assay called alk-BER to measure DNA alkylation damage and repair rates, offering a reliable and reproducible method for studying BER activity in various cell types.

This study shows that locus-coeruleus norepinephrine activity determines the likelihood of sensory-evoked awakenings from sleep, with reduced activity during sleep suppressing responses to auditory stimuli.

The paper shows that spinal and prefrontal projecting locus coeruleus neurons in rats mediate distinct pain-related behaviors: analgesia vs. aversion and anxiety.