Pituitary Tumor Transforming Gene 1 orchestrates gene regulatory variation in mouse ventral midbrain during aging
Yujuan Gui, Mélanie H. Thomas, Pierre Garcia, Mona Karout, Rashi Halder, Alessandro Michelucci, Heike Kollmus, Cuiqi Zhou, Shlomo K. Melmed, Klaus Schughart, Rudi Balling, Michel Guy André Mittelbronn, Joseph H. Nadeau, Robert W. Williams, Thomas Sauter, , Lasse Sinkkonen
The paper identifies Pttg1 as a key regulator of gene expression variation in mouse ventral midbrain across aging, showing its role in transcriptome shifts and cell-type-specific changes.
Frontiers in Genetics · Sep 23, 2020Peer-reviewedGenomics