Author

D. A. Nathanson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Bhaduri· 2 shared A. B. Ball· 1 shared A. E. Jones· 1 shared A. G. Alvarado· 1 shared A. J. Brownstein· 1 shared A. N. Murphy· 1 shared A. Neilson· 1 shared A. S. Divakaruni· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

A. Bhaduri

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Human Organoid Tumor Transplantation Identifies Functional Glioblastoma - Microenvironmental Communication Mediated by PTPRZ1

W. Ge, R. L. Kan, C. Yilgor, E. Fazzari, P. R. Nano, D. J. Azizad, M. Li, J. Y. Ito, C. Tse, H. A. Tum, J. Scholes, K. S. Patel, D. A. Nathanson, A. Bhaduri

The paper uses a human organoid tumor transplantation system to study glioblastoma-microenvironment interactions, identifying PTPRZ1 as a key mediator of intercellular communication.

bioRxiv · May 2, 2024 · PreprintCancer Biology

Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-κB/BRD2 Chromatin Complex

r. vadla, S. Miki, B. Taylor, D. Kawauchi, B. M. Jones, N. Nathwani, P. Pham, J. Tsang, D. A. Nathanson, F. B. Furnari

This study identifies the PTEN-NF-κB-BRD2 pathway as critical for glioblastoma mesenchymal transition and invasion, suggesting BET-BD2 inhibitors as a therapeutic strategy.

bioRxiv · Jul 3, 2023 · PreprintCancer Biology

Calculation of ATP production rates using the Seahorse XF Analyzer

B. R. Desousa, K. K. O. Kim, A. E. Jones, A. B. Ball, W. Y. Hsieh, P. Swain, D. H. Morrow, D. A. Ferrick, A. J. Brownstein, O. S. Shirihai, A. Neilson, D. A. Nathanson, G. W. Rogers, B. P. Dranka, A. N. Murphy, , A. S. Divakaruni

The paper develops a method to calculate ATP production rates from oxidative phosphorylation and glycolysis using Seahorse XF Analyzer data, enabling direct comparison of ATP sources in live cells.

bioRxiv · Apr 16, 2022Biochemistry

Pathway-based approach reveals differential sensitivity of glioblastoma to E2F1 inhibition

A. G. Alvarado, K. Tessema, S. D. Muthukrishnan, M. Sober, R. Kawaguchi, A. Bhaduri, V. Swarup, D. A. Nathanson, S. A. Goldman, H. I. Kornblum

This study uses pathway analysis to identify E2F1 as a key driver of glioblastoma proliferation and shows its inhibition sensitizes tumors to radiation.

bioRxiv · Jun 19, 2021Cancer Biology