Author

D. Eldershaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Liu· 2 shared S. Weeratunga· 2 shared A. Bademosi· 1 shared A. Jiang· 1 shared A. Malapaka· 1 shared B. Collins· 1 shared B. M. Collins· 1 shared B. Townsend· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

M. Liu

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4

G. T. Nguyen-Dien, B. Townsend, P. Kulkarni, K.-L. Kozul, S. S. Ooi, D. Eldershaw, S. Weeratunga, M. Liu, M. J. Jones, S. S. Millard, D. C. Ng, M. Pagano, D. Komander, M. Lazarou, B. M. Collins, J. K. Pagan

This study identifies PPTC7 as a cofactor for SCFFBXL4-mediated degradation of BNIP3 and NIX, suppressing mitophagy and revealing a feedback mechanism to regulate mitochondrial homeostasis.

bioRxiv · Feb 23, 2024Cell Biology

Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2

S. Weeratunga, R. Gormal, M. Liu, D. Eldershaw, E. Livingstone, A. Malapaka, T. Wallis, A. Bademosi, A. Jiang, M. Healy, F. Meunier, B. Collins

The paper uses AlphaFold2 to identify and validate interactions of Mint proteins with Munc18-1 and their broader interactome, revealing structural and functional insights into neuronal membrane trafficking.

bioRxiv · Feb 20, 2023Biochemistry