Author

M. J. Jones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Ecology· 2 Microbiology· 2 Pathology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:ecology & biodiversity· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

E. A. McGraw· 3 shared D. G. SIm· 2 shared A. A. King· 1 shared A. Andrew· 1 shared A. Diaz· 1 shared A. F. Read· 1 shared A. Huntsinger· 1 shared B. A. Biddlecombe· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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3 shared papersMicrobiology

E. A. McGraw

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Mechanism by which Aurora B inhibitors promotes RB and p53-dependent senescence.

S. Vora, A. Andrew, R. P. Kumar, D. Nazareth, M. Fernando, M. J. Jones, Y. He, J. Hooper, N. A. McMillan, J. Urosevic, J. Saeh, J. Travers, B. Gabrielli

This study investigates how Aurora B inhibitors induce polyploidy and shows that higher ploidy states reduce long-term proliferative potential in cells with functional RB and p53.

bioRxiv · Mar 27, 2024 · PreprintCell Biology

PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4

G. T. Nguyen-Dien, B. Townsend, P. Kulkarni, K.-L. Kozul, S. S. Ooi, D. Eldershaw, S. Weeratunga, M. Liu, M. J. Jones, S. S. Millard, D. C. Ng, M. Pagano, D. Komander, M. Lazarou, B. M. Collins, J. K. Pagan

This study identifies PPTC7 as a cofactor for SCFFBXL4-mediated degradation of BNIP3 and NIX, suppressing mitophagy and revealing a feedback mechanism to regulate mitochondrial homeostasis.

bioRxiv · Feb 23, 2024Cell Biology

Climate change, age acceleration, and the erosion of fitness in polar bears

L. Newediuk, E. S. Richardson, B. A. Biddlecombe, H. Kassim, L. Kathan, N. Lunn, L. R. Rivkin, O. E. Salama, C. Schmidt, M. J. Jones, C. J. Garroway

This study links climate change to accelerated epigenetic aging in polar bears, reduced fitness, and near-zero adaptive potential.

bioRxiv · Jan 5, 2024 · PreprintEcology

Jamestown Canyon Virus is transmissible by Aedes aegypti and is only moderately blocked by Wolbachia co-infection

M.-J. Lau, H. Dutra, M. J. Jones, B. McNulty, A. Diaz, F. Ware-Gilmore, E. A. McGraw

This study shows that Aedes aegypti can transmit Jamestown Canyon Virus (JCV) and that Wolbachia only moderately blocks JCV replication, suggesting distinct mechanisms for blocking negative-sense vs. positive-sense viruses.

bioRxiv · May 11, 2023 · PreprintPathology

Alpha-mannosidase-2 modulates arbovirus infection in a pathogen- and Wolbachia-specific manner in Aedes aegypti mosquitoes

N. Urakova, R. E. Joseph, A. Huntsinger, V. M. Macias, M. J. Jones, L. T. Sigle, M. Li, O. S. Akbari, Z. Xi, K. Lymperopoulos, R. T. Sayre, E. A. McGraw, J. L. Rasgon

This study shows that the mosquito gene Man2 affects arbovirus infection and Wolbachia interactions differently depending on the pathogen and Wolbachia strain.

bioRxiv · Mar 18, 2022 · PreprintMicrobiology

Transmission and protection against re-infection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate

D. R. Patel, C. J. Field, K. M. Septer, D. G. SIm, M. J. Jones, T. A. Heinly, E. A. McGraw, T. C. Sutton

This study evaluates transmission modes and immunity duration against SARS-CoV-2 in ferrets, finding direct contact transmission is efficient and immunity lasts at least 56 days, but intramuscular vaccination does not prevent upper respiratory tract infection.

bioRxiv · Nov 20, 2020Microbiology

Low light levels increase avoidance behaviour of diurnal fish species: Implications for road culverts

J. K. Keep, J. R. Watson, R. L. Cramp, M. J. Jones, M. A. Gordos, C. E. Franklin

The paper tests how low light levels in culverts affect fish behavior, finding diurnal species avoid dark areas and require ~100-200 lux to pass through, while most culverts lack sufficient light.

bioRxiv · Jan 7, 2020Zoology

Breaking down defenses: Quantitative analysis of malaria infection dynamics reveals distinct immune defense strategies

N. Wale, M. J. Jones, D. G. Sim, A. F. Read, A. A. King

This study quantifies immune defense strategies against malaria by analyzing parasite and RBC dynamics, revealing coordinated resource-directed strategies that benefit the host.

bioRxiv · Aug 17, 2019 · PreprintEcology