Author

S. Weeratunga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:protein structure· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:multiple species· 1

Frequent Co-Authors

B. Collins· 2 shared B. M. Collins· 2 shared D. Eldershaw· 2 shared M. Liu· 2 shared A. Bademosi· 1 shared A. D. Davidson· 1 shared A. Jiang· 1 shared A. Malapaka· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

B. Collins

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4

G. T. Nguyen-Dien, B. Townsend, P. Kulkarni, K.-L. Kozul, S. S. Ooi, D. Eldershaw, S. Weeratunga, M. Liu, M. J. Jones, S. S. Millard, D. C. Ng, M. Pagano, D. Komander, M. Lazarou, B. M. Collins, J. K. Pagan

This study identifies PPTC7 as a cofactor for SCFFBXL4-mediated degradation of BNIP3 and NIX, suppressing mitophagy and revealing a feedback mechanism to regulate mitochondrial homeostasis.

bioRxiv · Feb 23, 2024Cell Biology

Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2

S. Weeratunga, R. Gormal, M. Liu, D. Eldershaw, E. Livingstone, A. Malapaka, T. Wallis, A. Bademosi, A. Jiang, M. Healy, F. Meunier, B. Collins

The paper uses AlphaFold2 to identify and validate interactions of Mint proteins with Munc18-1 and their broader interactome, revealing structural and functional insights into neuronal membrane trafficking.

bioRxiv · Feb 20, 2023Biochemistry

ESCPE-1 Mediates Retrograde Endosomal Sorting of the SARS-CoV-2 Host Factor Neuropilin-1

B. Simonetti, J. L. Daly, L. Simon-Gracia, K. Klein, S. Weeratunga, C. Anton-Plagaro, A. Tobi, L. Hodgson, P. Lewis, K. J. Heesom, D. K. Shoemark, A. D. Davidson, B. M. Collins, T. Teesalu, Y. Yamauchi, P. J. Cullen

The paper identifies Neuropilin-1 as a retrograde cargo of ESCPE-1 and shows ESCPE-1 mediates its trafficking, potentially facilitating SARS-CoV-2 infection.

bioRxiv · Jan 20, 2022Cell Biology

Structural predictions of the SNX-RGS proteins suggest they belong to a new class of lipid transfer proteins

B. Paul, S. Weeratunga, V. A. Tillu, H. Hariri, W. M. Henne, B. Collins

The paper uses AlphaFold2 to predict the structure of SNX-RGS proteins, revealing a new class of lipid transfer proteins with a conserved hydrophobic pocket.

bioRxiv · Nov 30, 2021Biochemistry