Author

K.-L. Kozul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. D. Attie· 1 shared B. M. Collins· 1 shared B. Townsend· 1 shared C. Balnis· 1 shared D. C. Ng· 1 shared D. Eldershaw· 1 shared D. J. Pagliarini· 1 shared D. Komander· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. D. Attie

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4

G. T. Nguyen-Dien, B. Townsend, P. Kulkarni, K.-L. Kozul, S. S. Ooi, D. Eldershaw, S. Weeratunga, M. Liu, M. J. Jones, S. S. Millard, D. C. Ng, M. Pagano, D. Komander, M. Lazarou, B. M. Collins, J. K. Pagan

This study identifies PPTC7 as a cofactor for SCFFBXL4-mediated degradation of BNIP3 and NIX, suppressing mitophagy and revealing a feedback mechanism to regulate mitochondrial homeostasis.

bioRxiv · Feb 23, 2024Cell Biology

Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy

N. M. Niemi, L. R. Serrano, L. K. Muehlbauer, C. Balnis, K.-L. Kozul, E. H. Rashan, E. Shishkova, K. L. Schueler, M. P. Keller, A. D. Attie, J. Pagan, J. J. Coon, D. J. Pagliarini

This study shows that Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy, leading to metabolic defects and early lethality in mice.

bioRxiv · Feb 28, 2023Biochemistry