Author

S. A. Johnston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:zebrafish· 3 Research Focus:cell signaling & trafficking· 2 Assay:imaging· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. F. Gibson· 2 shared J. J. Serba· 2 shared S. A. Renshaw· 2 shared T. K. Prajsnar· 2 shared A. Bojarczuk· 1 shared A. Fleming· 1 shared A. H. Meijer· 1 shared A. J. Grierson· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

J. F. Gibson

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Candida spp. suppress neutrophil reactive nitrogen species to evade killing

T. B. Burgess, F. R. Hammond, P. T. Szkuta, A. Lewis, S. Christou, K. A. Bowden, T. Bicanic, L. Prince, K. R. Ayscough, D. G. Partridge, S. A. Johnston, A. M. Condliffe, P. M. Elks

This study shows that Candida spp. suppress neutrophil reactive nitrogen species to evade killing, and restoring RNS via Hif-1 stabilisation improves infection outcomes.

bioRxiv · Nov 2, 2023Immunology

Neutrophils use selective autophagy receptor p62 to target Staphylococcus aureus for degradation in the zebrafish model

J. F. Gibson, T. K. Prajsnar, C. J. Hill, A. K. Tooke, J. J. Serba, R. D. Tonge, A. J. Grierson, P. W. Ingham, S. A. Renshaw, S. A. Johnston

This study shows p62 facilitates autophagy-mediated degradation of Staphylococcus aureus in zebrafish neutrophils.

bioRxiv · Feb 18, 2020Immunology

The mouse lung early cellular innate immune response is not sufficient to control fungal infection with Cryptococcus neoformans

J. Rudman, H. M. Marriott, L. M. Carlin, S. A. Johnston

This study uses an ex vivo mouse lung model to show that innate immune cells cannot control Cryptococcus neoformans infection and provide an intracellular niche for fungal growth.

bioRxiv · Jun 24, 2019 · PreprintImmunology

The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils

T. K. Prajsnar, J. J. Serba, B. M. Dekker, J. F. Gibson, S. Masud, A. Fleming, S. A. Johnston, S. A. Renshaw, A. H. Meijer

This study shows that S. aureus uses autophagy to create an intracellular niche in neutrophils, while p62-mediated autophagy protects the host.

bioRxiv · Mar 18, 2019 · PreprintImmunology

Inhibition of classical and alternative modes of respiration in C. albicans leads to cell wall remodelling and increased macrophage recognition

L. Duvenage, L. A. Walker, A. Bojarczuk, S. A. Johnston, D. M. MacCallum, C. A. Munro, C. Gourlay

This paper inhibits respiration in C. albicans using low-toxicity chemicals, leading to cell wall changes and increased macrophage recognition, but also enhancing virulence.

bioRxiv · May 24, 2018Microbiology

Simu-dependent clearance of dying cells regulates macrophage function and inflammation resolution

H. G. Roddie, E. L. Armitage, S. A. Johnston, I. R. Evans

This study shows that Simu-dependent clearance of apoptotic cells affects macrophage function and inflammation resolution in Drosophila embryos.

bioRxiv · May 1, 2018Cell Biology