Author

D. M. Nguyen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. F. A. Keszei· 1 shared A. X. Ji· 1 shared A. Zhai· 1 shared C. A. Maguire· 1 shared C. Ng· 1 shared C. Poveda· 1 shared D. A. Kuntz· 1 shared D. De La Cruz· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiochemistry

A. F. A. Keszei

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structure and dynamics of a pentameric KCTD5/Cullin3/Gβγ E3 ubiquitin ligase complex

D. M. Nguyen, D. H. Rath, D. Devost, D. Petrain, R. Rizk, A. X. Ji, N. Narayanan, D. Yong, A. Zhai, D. A. Kuntz, M. U. Q. Mian, N. C. Pomroy, A. F. A. Keszei, S. Benlekbir, M. T. Mazhab-Jafari, , G. G. Prive

The paper presents the cryo-EM structure of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex, revealing its dynamic architecture and mechanism for ubiquitylating Gβγ.

bioRxiv · Sep 20, 2023 · PreprintBiochemistry

In vivo selection in non-human primates identifies superior AAV capsids for on-target CSF delivery to spinal cord

K. S. Hanlon, M. Cheng, D. De La Cruz, N. Patel, M. C. Santoscoy, Y. Gong, C. Ng, D. M. Nguyen, J. Nammour, S. W. Clark, K. Kozarsky, C. A. Maguire

The paper identifies superior AAV capsids for targeted spinal cord gene therapy in non-human primates through in vivo selection and evaluates their biodistribution and expression.

bioRxiv · Sep 13, 2023 · PreprintBioengineering

The impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic Trypanosoma cruzi infection

K. Jones, D. M. Nguyen, C. Poveda, J. Pollet, F. Gusovsky, M. E. Bottazzi, P. J. Hotez

This study evaluates the impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic Trypanosoma cruzi infection, finding that the treatment better preserves liver health compared to curative doses of benznidazole.

bioRxiv · Jul 11, 2023Pathology