Author

D. Mouradov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. S. Dhillon· 1 shared C. Darido· 1 shared C. M. Reehorst· 1 shared D. S. Williams· 1 shared E. Segelov· 1 shared F. Koentgen· 1 shared F. Tan· 1 shared H. Anderton· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

A. S. Dhillon

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2 papers

Recent·Most cited

SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss

X. Xi, L. Liu, N. Tuano, J. Tailhades, D. Mouradov, O. Sieber, M. Cryle, E. Segelov, J. Rosenbluh

The paper identifies SRP19 as a vulnerability in cancers with APC loss, showing that reducing SRP19 inhibits proliferation through ER stress.

bioRxiv · Jan 30, 2024 · PreprintCancer Biology

EHF is essential for epidermal and colonic epithelial homeostasis and suppresses Apc-initiated colonic tumorigenesis

C. M. Reehorst, R. Nightingale, I. Y. Luk, L. Jenkins, F. Koentgen, D. S. Williams, C. Darido, F. Tan, H. Anderton, M. Chopin, K. Schoffer, M. F. Eissmann, M. Buchert, D. Mouradov, O. M. Sieber, , J. M. Mariadason

This study shows that EHF is essential for epidermal and colonic epithelial homeostasis and acts as a tumor suppressor in colorectal cancer.

bioRxiv · Mar 1, 2021Cell Biology