Author

C. M. Reehorst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

I. Y. Luk· 2 shared J. M. Mariadason· 2 shared M. Buchert· 2 shared R. Nightingale· 2 shared A. Ahrorov· 1 shared A. Esmaeilniakooshkghazi· 1 shared A. S. Dhillon· 1 shared A. S. Yap· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

I. Y. Luk

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Beclin1 is essential for intestinal homeostasis.

S. Tran, J. Juliani, T. J. Harris, M. Evangelista, J. Ratcliffe, S. L. Ellis, D. Baloyan, C. M. Reehorst, R. Nightingale, I. Y. Luk, L. J. Jenkins, S. Ghilas, M. H. Yakou, C. Inguanti, C. Johnson, , E. F. Lee

This study shows BECLIN1 is critical for intestinal homeostasis, as its deletion in adult mice causes fatal enteritis with compromised gut barrier integrity and morphological abnormalities.

bioRxiv · Jun 14, 2023 · PreprintCell Biology

In colon cancer cells, fascin1 functions as a mechanosensor that transforms adherens junction mechanotransduction.

A. Esmaeilniakooshkghazi, E. Pham, S. P. George, A. Ahrorov, F. R. Villagomez, M. Byington, S. Mukhopadhyay, S. Patnaik, J. C. Conrad, M. Naik, S. Ravi, N. Tebbuttt, J. Mooi, C. M. Reehorst, J. M. Mariadason, S. Khurana

This study identifies fascin1 as a mechanosensor in colon cancer cells that modulates adherens junction plasticity, promoting tumor growth and metastasis.

bioRxiv · Jun 14, 2022 · PreprintCancer Biology

EHF is essential for epidermal and colonic epithelial homeostasis and suppresses Apc-initiated colonic tumorigenesis

C. M. Reehorst, R. Nightingale, I. Y. Luk, L. Jenkins, F. Koentgen, D. S. Williams, C. Darido, F. Tan, H. Anderton, M. Chopin, K. Schoffer, M. F. Eissmann, M. Buchert, D. Mouradov, O. M. Sieber, , J. M. Mariadason

This study shows that EHF is essential for epidermal and colonic epithelial homeostasis and acts as a tumor suppressor in colorectal cancer.

bioRxiv · Mar 1, 2021Cell Biology