Author

J. M. Mariadason

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 2 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

C. M. Reehorst· 2 shared I. Y. Luk· 2 shared M. Ernst· 2 shared R. Nightingale· 2 shared A. Ahrorov· 1 shared A. Dhillon· 1 shared A. Esmaeilniakooshkghazi· 1 shared A. S. Dhillon· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

C. M. Reehorst

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In colon cancer cells, fascin1 functions as a mechanosensor that transforms adherens junction mechanotransduction.

A. Esmaeilniakooshkghazi, E. Pham, S. P. George, A. Ahrorov, F. R. Villagomez, M. Byington, S. Mukhopadhyay, S. Patnaik, J. C. Conrad, M. Naik, S. Ravi, N. Tebbuttt, J. Mooi, C. M. Reehorst, J. M. Mariadason, S. Khurana

This study identifies fascin1 as a mechanosensor in colon cancer cells that modulates adherens junction plasticity, promoting tumor growth and metastasis.

bioRxiv · Jun 14, 2022 · PreprintCancer Biology

EHF is essential for epidermal and colonic epithelial homeostasis and suppresses Apc-initiated colonic tumorigenesis

C. M. Reehorst, R. Nightingale, I. Y. Luk, L. Jenkins, F. Koentgen, D. S. Williams, C. Darido, F. Tan, H. Anderton, M. Chopin, K. Schoffer, M. F. Eissmann, M. Buchert, D. Mouradov, O. M. Sieber, , J. M. Mariadason

This study shows that EHF is essential for epidermal and colonic epithelial homeostasis and acts as a tumor suppressor in colorectal cancer.

bioRxiv · Mar 1, 2021Cell Biology

Dual MAPK and HDAC inhibition rewires the apoptotic rheostat to trigger colorectal cancer cell death

L. J. Jenkins, I. Y. Luk, M. Palmieri, W. D. Fairlie, E. F. Lee, K. L. Schoffer, T. Tan, I. Ng, N. Vukelic, J. W. Tse, R. Nightingale, Z. Alam, G. Iatropoulos, M. Ernst, S. Afshar-Sterle, , J. M. Mariadason

This study shows that combining MEK/ERK and HDAC inhibition synergistically induces apoptosis in colorectal cancer cells and organoids, and can be tailored to specific MAPK genotypes.

bioRxiv · Feb 15, 2021 · PreprintCancer Biology